| 100% | ASP | 3 | Its bite is said to have killed Cleopatra |
| 72% | ASP | 3 | Snake that is said to have killed Cleopatra |
| 48% | INDY | 4 | Character who says, "Snakes. Why did it have to be snakes?" |
| 48% | LISP | 4 | Speech impediment whose name is hard to say if you have it |
| 47% | NINELIVES | 9 | What cats are said to have |
| 47% | SIDES | 5 | Every story is said to have two |
| 46% | NAPLES | 6 | Where pizza is said to have been invented |
| 46% | NINE | 4 | Number of lives cats are said to have |
| 46% | LIVES | 5 | Cats are said to have nine of them |
| 45% | STMARK | 6 | He is said to have founded the Church of Alexandria |
| 44% | OMAHA | 5 | Nebraska city where the Reuben is said to have been invented |
| 44% | WIT | 3 | Sarcasm is said to be the lowest form of it |
| 44% | THEPLUNGE | 9 | It's said to be taken upon marriage |
| 43% | PITCH | 5 | It has the potential to be a hit |
| 43% | SPOKANE | 7 | Northwestern city where Father's Day is said to have been born |
| 42% | AGE | 3 | It's said to be "just a number" |
| 41% | LIGHT | 5 | It is said to travel at 299,792,458 metres per second |
| 41% | ETNA | 4 | The monster Typhon was said to be trapped under it, in Greek myth |
| 40% | PEN | 3 | It's said to be mightier than a sword, in a proverb |
| 40% | WHOELSE | 7 | "Didn't it have to be me?" |
| 40% | HALLEYSCOMET | 12 | *Celestial sight said to have been a good omen for William the Conqueror in battle |
| 37% | DID | 3 | "Why ___ It Have To Be Me?" (ABBA tune) |
| 36% | BULLET | 6 | Bit of ammo that one might want to "dodge" and has a "bull" in its name |
| 36% | DYEPURRS | 8 | *Indications that a cat is happy that its fur changed from gray to green, say? |
| 36% | IMDUE | 5 | "It has to be my turn soon" |
| 35% | ARESO | 5 | Potential reply to "I am not a crook," if you assume Nixon said it on a playground |
| 35% | ANNIEHALL | 9 | Title character who sings "It Had to Be You" |
| 34% | RED | 3 | What mad people are said to see |
| 34% | GARLIC | 6 | Vampires are said to hate this root |
| 34% | IDO | 3 | It’s said to wed |