| 100% | ROTUNDA | 7 | Jeffersonian design at the heart of the University of Virginia |
| 49% | POE | 3 | Writer whose room at the University of Virginia is now a mini-museum |
| 48% | AMID | 4 | At the heart of |
| 48% | CIRCLE | 6 | Shape at the heart of the flags of Japan and Laos |
| 45% | DAMSQUARE | 9 | Public space at the heart of Amsterdam |
| 45% | COLD | 4 | Temperature firm at the heart of mildew |
| 45% | RNA | 3 | Genetic component at the heart of hibernation? |
| 45% | GETTO | 5 | "___ the heart of the matter." (arrive at): 2 wds. |
| 45% | EDU | 3 | Letters at the end of most university websites |
| 45% | ZEE | 3 | What's at the heart of every calzone? |
| 45% | YANGMILLS | 9 | Gauge theory at the heart of Standard Model |
| 45% | CITADEL | 7 | Fortified area at the heart of a settlement |
| 45% | APPLEPIP | 8 | Seed at the heart of a Granny Smith |
| 44% | BLACKSTAR | 9 | Emblem at the heart of Ghana's national flag |
| 44% | WOODHOUSE | 9 | Family at the heart of Jane Austen's Emma |
| 44% | ENRON | 5 | Company at the heart of an early 2000s scandal |
| 44% | TREASUREMAP | 11 | Drawing at the heart of many a pirate story |
| 44% | TULIP | 5 | Flower at the heart of a 1637 financial crisis |
| 44% | ARTICLE | 7 | What is found at the heart of this clue |
| 44% | PENNSTATE | 9 | University at the foothills of Mount Nittany |
| 44% | TIKIBARBER | 10 | NFL running back who played alongside his twin brother, Ronde, at the University of Virginia and on three Pro Bowl teams: 2 wds. |
| 44% | PEARSONS | 8 | Family that's at the heart of "This Is Us" |
| 43% | DONS | 4 | Educators at the University of Oxford |
| 43% | WAFER | 5 | Thin slice of silicon at the heart of an integrated circuit |
| 43% | PEACHPIT | 8 | "Stone" at the heart of Georgia's state fruit: 2 wds. |
| 43% | NUKES | 5 | Weapons at the heart of a disputed U.S.-Russia treaty |
| 42% | RAGINCAJUNS | 11 | Athletes at the University of Louisiana at Lafayette |
| 42% | IQS | 3 | Scores developed at the University of Wrocław, briefly |
| 42% | LEIS | 4 | Graduation day wear at the University of Hawaii |
| 42% | GERARD | 6 | ___ Butler, Scottish actor who studied at the University of Glasgow School of Law |