| 100% | SPENCER | 7 | Jesse ___, actor who plays Dr. Robert Chase on "House, M.D." |
| 73% | LEONARD | 7 | Robert Sean ___, actor who plays Dr. James Wilson on "House, M.D." |
| 70% | JESSESPENCER | 12 | Australian actor who played Dr Robert Chase in US television series House |
| 69% | OMAR | 4 | ___ Epps, actor who plays Dr. Eric Foreman on "House, M.D." |
| 57% | MARKHARMON | 10 | "NCIS" actor who played Dr. Robert Caldwell on "St. Elsewhere": 2 wds. |
| 57% | HUGH | 4 | ___ Laurie, actor who plays Gregory House on "House, M.D." |
| 56% | OLIVERPLATT | 11 | "Huff" actor who plays Dr. Daniel Charles on "Chicago Med": 2 wds. |
| 54% | TEE | 3 | Actor Brian who plays Dr. Ethan Choi on "Chicago Med" |
| 52% | OMAR | 4 | With 39-Down, actor who plays Dr. Eric Foreman on "House" |
| 52% | LISAEDELSTEIN | 13 | Actress who plays Dr. Cuddy on "House, M.D.": 2 wds. |
| 52% | OMAR | 4 | With 38-Down, actor who played Dr. Eric Foreman on "House" |
| 51% | HUGHLAURIE | 10 | Actor who played Dr. Gregory House in "House" |
| 50% | OMAR | 4 | Actor Epps who plays Dr. Eric Foreman on "House" |
| 50% | OMAR | 4 | Actor Epps who played Dr. Eric Foreman on "House" |
| 49% | KELSEYGRAMMER | 13 | Actor who played Dr. Frasier Crane on "Frasier": 2 wds. |
| 49% | AARONPAUL | 9 | Actor who played Jesse on Breaking Bad |
| 49% | WILDE | 5 | Olivia ___, actress who plays Dr. Remy on "House, M.D." |
| 48% | ROBERTSEAN | 10 | With 25-Across, actor who played Dr. James Wilson (based on 47-Across) on the Fox series "House": 2 wds. |
| 48% | HUGH | 4 | Actor Laurie, who played the role of Dr. House in the show "House M.D" |
| 48% | EPPS | 4 | Omar —, actor who played Dr Eric Foreman in US television series House |
| 47% | HARRISONFORD | 12 | "1923" actor who plays Dr. Paul Rhoades on "Shrinking" (2 wds.) |
| 46% | RYANEGGOLD | 10 | "The Blacklist" actor who plays Dr. Max Goodwin on "New Amsterdam" (2 wds.) |
| 46% | JOHN | 4 | ___ Stamos, actor who plays Jesse Katsopolis in the 1987 sitcom "Full House" |
| 45% | OMIDABTAHI | 10 | "American Gods" actor who plays Dr. Pershing on "The Mandalorian" (2 wds.) |
| 45% | BURR | 4 | Raymond —, Canadian actor who played Perry Mason and Robert Ironside on television |
| 45% | STAMOS | 6 | John who played Uncle Jesse on “Full House” |
| 45% | WYLE | 4 | Actor Noah who plays Dr. Carter on "ER" |
| 45% | DANNYMCBRIDE | 12 | "Eastbound & Down" actor who plays Jesse Gemstone on "The Righteous Gemstones" (2 wds.) |
| 45% | HUGHLAURIE | 10 | British actor who played American Gregory House on Fox's "House": 2 wds. |