| 100% | UNRUH | 5 | Jesse who lost to Ronald Reagan in 1970 |
| 78% | UNRUH | 5 | Jesse who lost the governor's race to Ronald Reagan in 1970 |
| 75% | UNRUH | 5 | California politico Jesse who lost to Reagan in 1970 |
| 43% | MITT | 4 | Romney who lost to Obama in 2012 |
| 43% | REA | 3 | Actor who lost to Pacino in 1993 |
| 42% | ALF | 3 | Landon who lost to F.D.R. in 1936 |
| 40% | RIGGS | 5 | Bobby who lost to Billie Jean King in tennis' "Battle of the Sexes" |
| 40% | HARE | 4 | One who lost to a tortoise in a fable? |
| 40% | HARE | 4 | One who lost to a tortoise in a fable |
| 39% | ALF | 3 | Landon who lost in a landslide to F.D.R. |
| 39% | HARE | 4 | Animal who lost to the tortoise in a fabled race |
| 39% | DROZ | 4 | Physician who lost to John Fetterman in a 2022 Senate race |
| 38% | HARE | 4 | Rabbit's kin who lost to a tortoise, in a popular fable |
| 38% | ISAO | 4 | Pro golfer Aoki who lost to Jack Nicklaus by two strokes in the 1980 U.S. Open |
| 38% | SONNYLISTON | 11 | Heavyweight champion who lost that title to 40-Across in 1964: 2 wds. |
| 38% | NICKNOLTE | 9 | Actor who lost the Oscar for Best Actor to Anthony Hopkins in 1992 |
| 38% | BORIS | 5 | Spassky who lost to Bobby Fischer in chess’s Match of the Century |
| 37% | URIEL | 5 | Angel who directs Satan to Earth in "Paradise Lost" |
| 37% | RIGGS | 5 | Bobby who lost to Billie Jean in the Battle of the Sexes tennis match |
| 37% | STEFANEDBERG | 12 | Swedish tennis great who lost to 25-Across in the 1990 Australian Open (2 wds.) |
| 36% | MICHAELMOORER | 13 | Boxer who lost to 43-Across in the 1994 bout billed as "One for the Ages" (2 wds.) |
| 35% | MATSWILANDER | 12 | Swedish tennis great who lost to 25-Across in the 1987 French Open and US Open (2 wds.) |
| 35% | PAM | 3 | Shriver who lost to Chris Evert in the 1978 US Open singles final when she was just 16 |
| 35% | DOLE | 4 | Bob who lost to Bill |
| 35% | BARRY | 5 | Goldwater who lost to Johnson |
| 35% | ALF | 3 | Landon who lost to FDR |
| 35% | ALANRICKMAN | 11 | "Harry Potter" actor who plays President Ronald Reagan in "The Butler" (2 wds.) |
| 35% | EDMCMAHON | 9 | Johnny Carson sidekick who nearly lost his home to foreclosure in 2008: 2 wds. |
| 34% | GEORGEFOREMAN | 13 | Heavyweight champion who lost that title to 40-Across in 1974's famous "Rumble in the Jungle": 2 wds. |
| 34% | GANDHI | 6 | Who said "The best way to find yourself is to lose yourself in the service of others" |