| 100% | PROFILES | 8 | John F. Kennedy’s “___ in Courage” |
| 69% | ETHEL | 5 | John F. Kennedy's sister-in-law |
| 66% | USNAVY | 6 | John F. Kennedy and Jimmy Carter served in it |
| 63% | JACQUELINE | 10 | John f. kennedy's wife |
| 63% | BARACKOBAMA | 11 | Former U.S. President honored with the 2017 John F. Kennedy Profile in Courage Award (2 wds.) |
| 61% | GEORGE | 6 | John F. Kennedy Jr.'s magazine |
| 60% | JAMESMARSDEN | 12 | "X-Men" actor who plays John F. Kennedy in "The Butler": 2 wds. |
| 57% | LYNDONBJOHNSON | 14 | US vice president who became president upon the death of John F. Kennedy in 1963: 3 wds. |
| 56% | NANCYPELOSI | 11 | Speaker of the House honored with the 2019 John F. Kennedy Profile in Courage Award (2 wds.) |
| 55% | SWEETCAROLINE | 13 | Neil Diamond song inspired by John F. Kennedy's daughter (2 wds.) |
| 54% | ROBERTFROST | 11 | Poet who read "The Gift Outright" at John F. Kennedy's inauguration (2 wds.) |
| 54% | MITCHLANDRIEU | 13 | Former mayor of New Orleans honored with the 2018 John F. Kennedy Profile in Courage Award (2 wds.) |
| 53% | UNCLE | 5 | John F. Kennedy, to Maria Shriver |
| 52% | BAREXAM | 7 | John F. Kennedy, Jr., failed it twice |
| 52% | LYNDONJOHNSON | 13 | Texan who resigned his Senate seat to become John F. Kennedy's vice president: 2 wds. |
| 52% | LAGUARDIA | 9 | Alternative to John F. Kennedy |
| 52% | LOGAN | 5 | Frequent John F. Kennedy connection |
| 51% | GEMINI | 6 | John F. Kennedy or George H. W. Bush |
| 51% | DEM | 3 | John F. Kennedy or Barack Obama, politically: Abbr. |
| 51% | NIECE | 5 | Maria Shriver, to John F. Kennedy |
| 51% | AIRCRAFTCARRIER | 15 | USS John F. Kennedy, for one |
| 51% | KENNEDY | 7 | John F. __ Airport in New York |
| 50% | ASKNOT | 6 | Start of a John F. Kennedy quote |
| 50% | DALLAS | 6 | City where John F. Kennedy was assassinated |
| 50% | USS | 3 | Letters before John F. Kennedy and Constitution |
| 50% | SHOT | 4 | John F Kennedy and Abraham Lincoln were both ___ by men with guns |
| 49% | THEGREATDEMOCRAT | 16 | Answer to 67-Across, per John F. Kennedy |
| 49% | ERA | 3 | Camelot ___ (term for the John F. Kennedy presidency) |
| 49% | EIN | 3 | "Ich bin ___ Berliner" (John F. Kennedy's speech) |
| 49% | SAHL | 4 | Humorist Mort who wrote jokes for John F. Kennedy |