| 45% | RYANREYNOLDS | 12 | Jason Bateman's costar in the 2011 movie "The Change-Up": 2 wds. |
| 45% | JOHNTRAVOLTA | 12 | Rene Russo's costar in the 1995 gangster comedy "Get Shorty": 2 wds. |
| 45% | KEVINCOSTNER | 12 | Rene Russo's costar in the 1996 romantic comedy "Tin Cup": 2 wds. |
| 45% | SETHROGEN | 9 | James Franco's costar in "The Interview": 2 wds. |
| 45% | JASONBATEMAN | 12 | Jennifer Aniston's costar in the 2010 romantic comedy/drama "The Switch": 2 wds. |
| 44% | VINCEVAUGHN | 11 | Jennifer Aniston's costar in the 2006 romantic comedy/drama "The Break-Up": 2 wds. |
| 44% | PIERCEBROSNAN | 13 | Rene Russo's costar in the 1999 romantic thriller "The Thomas Crown Affair": 2 wds. |
| 44% | ADAMSANDLER | 11 | Jennifer Aniston's costar in the 2011 romantic comedy "Just Go With It": 2 wds. |
| 44% | ERNIEHUDSON | 11 | Costar of 1984's "Ghostbusters" who had a cameo in the 2016 version: 2 wds. |
| 44% | GERARDBUTLER | 12 | Jennifer Aniston's costar in the 2010 romantic comedy/action film "The Bounty Hounter": 2 wds. |
| 43% | ONEEYEDWILLY | 12 | Legendary pirate who hid the treasure in "The Goonies": 2 wds. |
| 43% | MATTSMITH | 9 | British actor who costarred in the 2022 film "Morbius": 2 wds. |
| 43% | RAYCHARLES | 10 | "Hit the Road Jack" singer who has a solo in 1985's "We Are the World": 2 wds. |
| 42% | GABRIELBYRNE | 12 | Irish-born actor who costarred in the 2018 movie "Hereditary": 2 wds. |
| 42% | COLINFARRELL | 12 | Irish-born actor who costarred in the 2018 movie "Widows": 2 wds. |
| 42% | JESSEPLEMONS | 12 | "Killers of the Flower Moon" actor who costars in "Civil War": 2 wds. |
| 41% | JUDELAW | 7 | Costar of Robert Downey, Jr. in the Sherlock Holmes films: 2 wds. |
| 41% | JULIANNEHOUGH | 13 | "Dancing With the Stars" judge who costars in 18-Across: 2 wds. |
| 41% | JANELYNCH | 9 | "Glee" costar who played the main character's mother in the 2022 Broadway revival of 15-Across: 2 wds. |
| 41% | MARSAIMARTIN | 12 | "Black-ish" costar who voices the dachshund Liberty in "PAW Patrol: The Movie": 2 wds. |
| 41% | ROSIEPEREZ | 10 | "White Men Can't Jump" actress who costars in the NBC show "Rise": 2 wds. |
| 41% | BILLCOSBY | 9 | Comedian who was awarded the Spingarn Medal in 1985: 2 wds. |
| 40% | DATA | 4 | "The Goonies" role for Ke Huy Quan |
| 40% | ROBREINER | 9 | "All in the Family" costar who guest-starred as himself on "The Simpsons": 2 wds. |
| 40% | ANTHONYRAMOS | 12 | "In the Heights" actor who costars in the new disaster movie "Twisters": 2 wds. |
| 40% | SAMROCKWELL | 11 | "Fosse/Verdon" actor who costars in the new spy comedy "Argylle": 2 wds. |
| 40% | WALTERMATTHAU | 13 | Jack Lemmon's costar in 18- and 37-Across: 2 wds. |
| 40% | JENNIFERLOPEZ | 13 | Ben Affleck's costar in "Gigli" and "Jersey Girl": 2 wds. |
| 40% | SCARLETTOHARA | 13 | Vivien Leigh's role in "Gone With the Wind": 2 wds. |
| 40% | RHETTBUTLER | 11 | Clark Gable's role in "Gone With the Wind": 2 wds. |