| 100% | EMCEE | 5 | Kevin Hart, for the Comedy Central roast of Justin Bieber |
| 37% | INSULTS | 7 | Most of the jokes at a Comedy Central Roast |
| 32% | MEATTHERMOMETER | 15 | Gadget for checking the temperature of a roast |
| 32% | EDUCATION | 9 | Central issue for the author of 15-Across |
| 32% | BABY | 4 | Justin Bieber hit that was the most-watched video on YouTube for a long time |
| 32% | ANDERSON | 8 | "Baywatch" actress Pamela ___ who was a roastee on Comedy Central Roast with Jimmy Kimmel as the roast master |
| 32% | FOVEA | 5 | Part of the eye responsible for sharp central vision |
| 32% | UMA | 3 | Actress Thurman of the romantic comedy "Playing for Keeps" |
| 32% | BIGTOBACCO | 10 | Subject of the 2006 comedy “Thank You for Smoking” |
| 32% | LIAR | 4 | Word repeated twice for the title of a legal comedy film starring Jim Carrey |
| 31% | UMA | 3 | Actress Thurman of the 2012 romantic comedy "Playing for Keeps" |
| 31% | ALONE | 5 | Like Kevin McCallister for much of the movie |
| 31% | MET | 3 | Colloquial term for the Central Park landmark which houses over two million works of art |
| 31% | BOBSAGET | 8 | "Fuller House" actor who was a roastee on Comedy Central Roast with John Stamos as the roast master: 2 wds. |
| 31% | JAMESFRANCO | 11 | "The Interview" star who was the subject of a Comedy Central Roast in 2013: 2 wds. |
| 31% | DONALDTRUMP | 11 | "The Apprentice" host who was the subject of a Comedy Central Roast in 2011: 2 wds. |
| 31% | ROSEANNEBARR | 12 | 1990s sitcom star who was the subject of a Comedy Central Roast in 2012: 2 wds. |
| 31% | ARKHAM | 6 | With 33-Across, institution for the criminally insane that is central to the plot of "Gotham" |
| 31% | FARCE | 5 | "The Comedy of Errors," for one |
| 30% | DONALDTRUMP | 11 | "The Apprentice" host who was the honoree of a 2011 Comedy Central roast: 2 wds. |
| 30% | PEGG | 4 | Simon —, star of 2014 comedy-drama film Hector and the Search for Happiness |
| 30% | CHARLIESHEEN | 12 | "Anger Management" star who was the honoree of a 2011 Comedy Central roast: 2 wds. |
| 30% | BELIEBER | 8 | Devoted fan of Justin Bieber |
| 30% | CHARLIESHEEN | 12 | "Two and a Half Men" actor who was a roastee on Comedy Central Roast with Seth MacFarlane as the roast master: 2 wds. |
| 29% | BROWN | 5 | "Murphy ___," winner of the 1990 Golden Globe for Best Musical or Comedy TV Series |
| 29% | TIMBERLAKE | 10 | Justin ___, singer who won Video of the Year for "Mirrors" at MTV Video Music Awards in 2013 |
| 29% | BELIEBERS | 9 | Followers and fans of Justin Bieber |
| 29% | BOB | 3 | "Full House" star Saget who was the honoree of a 2008 Comedy Central roast |
| 29% | TEEN | 4 | Justin Bieber, for example |
| 29% | SAKE | 4 | For the purpose of |