| 100% | LISALESLIE | 10 | L.A. Sparks player who was the first to dunk in a W.N.B.A. game |
| 60% | LISALESLIE | 10 | Basketball Hall of Fame inductee who was the first player to dunk in a WNBA game: 2 wds. |
| 56% | SWOOPES | 7 | Sheryl who was the first W.N.B.A. player to have a signature shoe |
| 53% | SHOHEIOHTANI | 12 | Japanese MLB player who was the first player in history to be a pitcher and hitter in the All-Star Game, in 2021: 2 wds. |
| 49% | LARRYNANCE | 10 | Phoenix Suns player who was the first player to ever win the NBA Slam Dunk Contest in 1984: 2 wds. |
| 48% | WILT | 4 | ___ Chamberlain, American basketball player who is the only player to score 100 points in a single NBA game |
| 48% | METS | 4 | M.L.B. team that was the first to trade a player for himself (Harry Chiti in 1962) |
| 48% | LISA | 4 | ___ Leslie, the first player to dunk in a WNBA game |
| 47% | LISA | 4 | ___ Leslie, the first player ever to dunk in a WNBA game |
| 47% | RUDOLPH | 7 | Wilma ___, late American sprinter who was the first American woman to win three gold medals in a single Olympic Games |
| 46% | LISALESLIE | 10 | First player to dunk in a WNBA game |
| 45% | JACKIESTILES | 12 | 2016 Women's Basketball Hall of Fame inductee who was the first Division I player to score over 1,000 points in a season: 2 wds. |
| 45% | DIAMONDJIMBRADY | 15 | Tycoon who was the first person in New York City to own a car |
| 45% | ITO | 3 | Olympic skater who was the first woman to land a triple axel in competition |
| 45% | ITO | 3 | Skater Midori who was the first woman to land a triple axel in competition |
| 44% | BLACKWELL | 9 | Elizabeth ___, British physician who was the first woman to earn a medical degree in the US |
| 44% | CARL | 4 | Nassib who was the first openly gay player in an NFL game |
| 44% | BRYANT | 6 | Kobe ___, former Los Angeles Lakers player who was the first guard to play 20 seasons in NBA |
| 44% | BARRY | 5 | ___ Nelson, American actor who was the first to portray James Bond in a television series titled "Climax!" |
| 43% | LESLIE | 6 | First player to make a slam dunk in a WNBA game |
| 43% | TED | 3 | Williams who was the last MLB player to hit over .400 in a season |
| 43% | REBA | 4 | McEntire who is the first woman to portray Colonel Sanders in a KFC ad |
| 43% | MARGARETCOURT | 13 | Australian tennis player who was the first woman to win the Grand Slam in the Open Era: 2 wds. |
| 43% | BARBARA | 7 | ___ A. Williams, American radio astronomer who was the first African-American woman to gain a PhD in Astronomy |
| 43% | DICKBUTTON | 10 | *Olympic champion who, in 1948, was the first to land a double axel in competition |
| 43% | ANNMEYERS | 9 | Basketball Hall-of-Famer who was the first woman to sign an N.B.A. contract |
| 43% | XXXXXXXX | 8 | Like a poker player who keeps getting everyone to fold before the first bet is made? |
| 43% | FREEMAN | 7 | Cathy ___, sprinter who was the first Australian indigenous person to become a Commonwealth Games gold medalist |
| 42% | RYUN | 4 | Jim ___, athlete who was the first high school junior to run a mile in under four minutes |
| 42% | UNO | 3 | Game in which the object is to be the first player to score 500 points |