| 100% | MUSKET | 6 | Large gun from the 16th century |
| 59% | MUSKET | 6 | A muzzle-loading firearm from the 16th century |
| 45% | MDI | 3 | Start of the 16th century |
| 44% | CALVIN | 6 | French reformer of the 16th century, John __ |
| 44% | SEAPOWERS | 9 | Spain and England in the 16th century |
| 43% | PORTUGAL | 8 | A big maritime potence of the 16th century |
| 43% | CHOPINES | 8 | High platform shoes worn in the 16th century |
| 43% | AMBROISE | 8 | __ Paré, French royal surgeon in the 16th century |
| 42% | SAHARAN | 7 | From the world's largest hot desert |
| 42% | ASIAN | 5 | Person from the largest continent |
| 42% | ASIAN | 5 | Someone from the largest continent |
| 42% | INCA | 4 | Member of an empire that ended in the 16th century |
| 42% | SIKH | 4 | Member of an Indian religion founded in the 16th century |
| 41% | LIAO | 4 | Chinese dynasty from the 10th - 12th century |
| 41% | ASIANS | 6 | People from the largest continent are called __ |
| 40% | ERNANI | 6 | 1844 opera by Giuseppe Verdi set in Spain in the 16th century |
| 40% | ANGLE | 5 | Member of a people from north Germany who invaded and settled large parts of England in the 5th and 6th centuries |
| 40% | SICILIAN | 8 | Describes a person from the largest Italian island |
| 39% | EDO | 3 | Japanese historical period from the 17th to 19th centuries |
| 39% | RAY | 3 | Beam of light from the sun or a laser gun |
| 39% | AWAY | 4 | "Take My Breath ___" (single from the "Top Gun" soundtrack album) |
| 39% | AMAZONECHO | 10 | Voice-controlled device from the world's largest online retailer |
| 38% | TUT | 3 | Egyptian king from the 14th century BC |
| 37% | INCA | 4 | Estimated to be the largest empire in the world in the early 16th century |
| 36% | AZTEC | 5 | Member of a Mexican Indian people whose great empire was overthrown by Hernan Cortes in the 16th century |
| 36% | STTERESA | 8 | __ of Ávila, canonized in the 16th-century |
| 36% | AMATI | 5 | Family of violin makers active in Cremona, Italy in the 16th and 17th centuries |
| 34% | NAVAJOS | 7 | Members of a large tribe from the southwestern US |
| 34% | BERNESE | 7 | __ Mountain Dog, large breed from the Swiss Alps |
| 34% | CROC | 4 | Large reptile that hunts from the water |