| 100% | CROWNE | 6 | Larry __; 2011 romantic comedy with Tom Hanks |
| 50% | BURBS | 5 | 1989 Tom Hanks black comedy, with "The" |
| 47% | LARRYCROWNE | 11 | Title role played by Tom Hanks in a 2011 romantic comedy: 2 wds. |
| 47% | ADAMSANDLER | 11 | Jennifer Aniston's costar in the 2011 romantic comedy "Just Go With It": 2 wds. |
| 46% | SEATTLE | 7 | "Sleepless in ___," 1993 romantic comedy film starring Tom Hanks and Meg Ryan |
| 46% | TERMINAL | 8 | 2004 comedy starring Tom Hanks set in an airport, with "The" |
| 45% | GOTMAIL | 7 | "You've ___," 1998 romantic comedy film starring Tom Hanks and Meg Ryan: 2 wds. |
| 42% | FORREST | 7 | __ Gump, movie with Tom Hanks |
| 42% | BIG | 3 | Tom Hanks comedy |
| 41% | GREENMILE | 9 | Tom Hanks film, with "The" |
| 40% | AMELIE | 6 | 2001 French romantic comedy with five Oscar nominations |
| 40% | BIG | 3 | 1988 Tom Hanks comedy |
| 40% | VOLUNTEERS | 10 | 1985 Tom Hanks comedy |
| 39% | LEAGUE | 6 | A __ of Their Own with Tom Hanks and Madonna |
| 39% | GUMP | 4 | Tom Hanks starrer comedy-drama film "Forrest ___" |
| 39% | YEMEN | 5 | "Salmon Fishing in ___," 2011 romantic comedy-drama starring Emily Blunt |
| 38% | THEBIGYEAR | 10 | 2011 birdwatching comedy with 41-Across: 3 wds. |
| 38% | BURBS | 5 | 1989 Tom Hanks film, with "The" |
| 38% | GREENMILE | 9 | 1999 Tom Hanks film, with "The" |
| 38% | MAIL | 4 | "You've Got ___," 1998 romcom with Tom Hanks and Meg Ryan |
| 38% | BIT | 3 | "A Little ___ of Heaven," a 2011 romantic comedy starring Kate Hudson |
| 38% | BAD | 3 | "___ Teacher," 2011 romantic comedy film starring Cameron Diaz and Jason Segel |
| 38% | GUMP | 4 | "Forrest ___," Tom Hanks starrer comedy-drama film |
| 37% | LOVE | 4 | "Crazy, Stupid, ___," 2011 romantic comedy film starring Julianne Moore and Steve Carell |
| 37% | OTTO | 4 | “A Man Named ___” (2022 Tom Hanks comedy-drama) |
| 37% | HES | 3 | "___ Just Not That Into You," a 2009 romantic comedy with an ensemble cast |
| 36% | BIGBUSINESS | 11 | Box-office receipts for a 1988 Tom Hanks comedy? |
| 36% | BIG | 3 | 1988 Tom Hanks film with a fortune-telling machine |
| 36% | SEATTLE | 7 | "Sleepless in ___" Tom Hanks film with 2 Oscar nominations |
| 36% | BIG | 3 | 1988 Tom Hanks movie with a giant piano keyboard |