| 100% | BIRO | 4 | Laszlo —, Hungarian journalist who patented the first practical ballpoint pen |
| 85% | BIRO | 4 | Laszlo —, Hungarian journalist who patented the first practical ball-point pen |
| 70% | BIRO | 4 | Laszlo —, Hungarian who patented the first practical ball-point pen |
| 39% | ASPDIN | 6 | William who patented the first artificial cement |
| 39% | BAUER | 5 | Eddie who patented the first quilted down jacket |
| 37% | COURIC | 6 | Journalist who was the first woman to guest-host "Jeopardy!" |
| 36% | CHARLESKURALT | 13 | Journalist who was the first host of 48-Across (2 wds.) |
| 36% | KATIECOURIC | 11 | Journalist who was the first woman to guest-host "Jeopardy!" (2 wds.) |
| 29% | ELI | 3 | Whitney who patented the cotton gin |
| 29% | ELIAS | 5 | Howe who patented the lockstitch sewing machine |
| 28% | WANKEL | 6 | Felix, who patented the rotary engine in 1954 |
| 28% | OLE | 3 | Evinrude, who in 1907 invented the first practical and commercial outboard motor |
| 28% | KARLBENZ | 8 | German engineer who designed and built the first practical automobile (1885) |
| 27% | NANCYDREW | 9 | Fictional young female detective who first appeared in a 1930 book credited to the pen name Carolyn Keene: 2 wds. |
| 27% | ORLANDO | 7 | The first name of the actor who played Legolas |
| 26% | ALYN | 4 | Kirk ___, the first actor who played Superman |
| 26% | HARDYBOYS | 9 | Fictional young male detectives who first appeared in a 1927 book credited to the pen name Franklin W Dixon: 2 wds. |
| 26% | PYLE | 4 | Journalist who wrote the 1943 book "Here Is Your War" |
| 26% | WHITTAKER | 9 | Jodie __, she plays the first female Doctor Who |
| 26% | OBAMA | 5 | First Lady who penned ''Becoming'' (2018) |
| 26% | URBANII | 7 | Pope who started the First Crusade |
| 26% | URBANII | 7 | Pope who initiated the First Crusade |
| 26% | JESSICABRUDER | 13 | Journalist who wrote the nonfiction bestseller 45-Across, which is subtitled "Surviving America in the Twenty-First Century" (2 wds.) |
| 25% | IDA | 3 | ___ B. Wells-Barnett, journalist who co-founded the NAACP |
| 25% | TELEPHONE | 9 | Alexander Graham Bell was the first to patent it |
| 25% | BLY | 3 | Journalist Nellie who went around the world |
| 25% | ANN | 3 | Journalist Curry who hosts "Chasing the Cure" |
| 25% | DOLLY | 5 | Sheep who was the first cloned mammal |
| 25% | EMIL | 4 | Jannings who won the first-ever Oscar |
| 25% | KELLY | 5 | Clarkson who won the first "American Idol" |