| 100% | NED | 3 | Lead character on "Pushing Daisies" |
| 63% | JAROD | 5 | Lead character on TV's "The Pretender" |
| 63% | ZACK | 4 | Lead character on "Saved by the Bell" |
| 62% | TED | 3 | Lead character on "How I Met Your Mother" |
| 61% | LEEPACE | 7 | Actor who played Ned on Pushing Daisies |
| 61% | BRODY | 5 | Lead character on the first three seasons of "Homeland" |
| 59% | PRAYTELL | 8 | Phrase expressing incredulity (and a lead character on "Pose") |
| 59% | TWENTYSOMETHING | 15 | Like the lead characters on “Insecure” and “Broad City” |
| 58% | ZACK | 4 | ___ Morris, lead character on TV's "Saved by the Bell" |
| 56% | LGBT | 4 | Like most of the lead characters on TV's "Queer as Folk" |
| 55% | JED | 3 | Name shared by lead characters on "The Beverly Hillbillies" and "The West Wing" |
| 54% | KRINGLE | 7 | Kris, the lead character in Miracle on 34th Street |
| 54% | TULLIVER | 8 | Maggie __, lead character in The Mill on the Floss |
| 54% | LAURAINGALLS | 12 | Lead character on TV's "Little House on the Prairie," played by Melissa Gilbert: 2 wds. |
| 52% | PIPERCHAPMAN | 12 | Lead character played by Taylor Schilling on "Orange Is the New Black": 2 wds. |
| 50% | POPE | 4 | Olivia ___ (lead character on TV's "Scandal") |
| 47% | CHRISTIANKANE | 13 | The actor who plays the lead character and genius Jacob Stone on "The Librarians": 2 wds. |
| 46% | ALPHA | 5 | Lead character? |
| 46% | INITIAL | 7 | Lead character |
| 46% | ALPHA | 5 | Leading character |
| 45% | NILESCRANE | 10 | Character on "Frasier" |
| 45% | ROSS | 4 | Character on "Friends" |
| 45% | ELAINE | 6 | Character on "Seinfeld" |
| 45% | MAINPROTAGONIST | 15 | Leading character, redundantly |
| 44% | ZEE | 3 | Lead character in Zola? |
| 43% | HOMER | 5 | Lead character in "The Simpsons" |
| 43% | ESS | 3 | Lead character in "Stranger Things"? |
| 43% | EMS | 3 | Lead characters in "Mork & Mindy"? |
| 43% | EMS | 3 | Lead characters in Marley & Me? |
| 43% | EMS | 3 | Lead characters in "Mike & Molly"? |