| 100% | MCCARTNEY | 9 | Left-handed guitarist who once played “Twenty Flight Rock” on an upside-down right-handed guitar to impress a future bandmate |
| 29% | BIRD | 4 | Larry ___, basketballer who once played most of a game with his left hand |
| 27% | ARROWKEY | 8 | It's pressed to go left, right, up or down on a computer |
| 25% | SAMUELLJACKSON | 14 | "Snakes on a Plane" actor who wore an eyepatch to play Nick Fury in many Marvel movies: 3 wds. |
| 25% | ALBERTKING | 10 | "Born Under a Bad Sign" blues musician who played guitar left-handed: 2 wds. |
| 25% | SWIPES | 6 | Left or right motions on Tinder to find a mate |
| 24% | WIDOW | 5 | To whom a husband leaves an estate |
| 24% | TORME | 5 | Singer who once sang a song to Kramer on "Seinfeld" |
| 24% | SWITCHHITTER | 12 | Term for 14-Across, a player who's able to bat both right- and left-handed: Hyph. |
| 23% | ARROWS | 6 | Up, down, left and right on a keyboard |
| 23% | OLSON | 5 | Johnny who used to cry "Come on down!" on "The Price Is Right" |
| 23% | FRANKBANK | 9 | Actor who played Lumpy on Leave It to Beaver |
| 23% | STRUM | 5 | The action needed to play a chord on guitar |
| 23% | ANGUS | 5 | With 33-Across, guitarist who played with his brother Malcolm on the AC/DC hit "Highway to Hell" |
| 23% | NATHANFILLION | 13 | "Firefly" actor who plays Officer John Nolan on an ABC series about a new LAPD cop (2 wds.) |
| 23% | TREBLE | 6 | Kind of clef preceding notes usually played with the right hand on a piano |
| 23% | ACROSS | 6 | Direction of a row; left to right, not up and down |
| 22% | AMBI | 4 | Prefix with "dextrous" to mean someone who uses both left and right hand with equal ease |
| 22% | STING | 5 | Rocker who plays himself, as a murder suspect, on "Only Murders in the Building" |
| 22% | LILLI | 5 | Actress Cooper who plays Doc on "Fraggle Rock: Back to the Rock" |
| 22% | ICET | 4 | "Cop Killer" singer who went on to play a cop on TV |
| 22% | FURY | 4 | Nick ___, Marvel character with an eye patch who is known to never turn his frown upside down |
| 22% | DANNYMCBRIDE | 12 | "Vice Principals" actor who played a former pro baseball player on "Eastbound & Down": 2 wds. |
| 22% | DANNYBONADUCE | 13 | Actor who played a guitar-playing sibling on "The Partridge Family" (2 wds.) |
| 22% | NEED | 4 | "I ___ to Know" (song by a rock artist who left us in 2017) |
| 22% | JAILHOUSEROCK | 13 | *Musical film about a convict who learns to play the guitar in prison |
| 22% | GROUCHO | 7 | Who once quipped “I never forget a face, but in your case I’ll be glad to make an exception" |
| 22% | ALT | 3 | Key to the left or right of the space bar on a Windows keyboard |
| 21% | INTERVIEWWHEEZE | 15 | Sound of a job seeker who ran hard to get to an appointment on time? |
| 21% | DAMIANLEWIS | 11 | English actor who spoke with an American accent to play Nicholas Brody on "Homeland": 2 wds. |