| 100% | PANETTA | 7 | Leon who was Obama's first C.I.A. director |
| 49% | WOOLSEY | 7 | James who was C.I.A. director under Clinton |
| 49% | ERIC | 4 | Holder who was Obama's first attorney general |
| 48% | DOMEE | 5 | Shi who was the first woman to have the sole director’s credit on a Pixar feature, for “Turning Red” |
| 47% | LEON | 4 | Panetta who was Obama's CIA Director and Secretary of Defense |
| 47% | PANETTA | 7 | Obama’s C.I.A. director |
| 47% | MEANY | 5 | George who was the first president of the A.F.L.-C.I.O. |
| 46% | MEANY | 5 | Labor leader George who was the first president of the A.F.L.-C.I.O. |
| 44% | PANETTA | 7 | C.I.A. director under Obama |
| 44% | AVA | 3 | Director DuVernay who was the first African-American woman nominated for a Best Picture Oscar |
| 44% | AVA | 3 | Director DuVernay who was the first African American woman nominated for a Best Picture Oscar |
| 43% | ANG | 3 | Lee who was the first Asian to win a best-director Oscar |
| 43% | YODA | 4 | Sci-fi character who was originally a puppet before C.G.I. |
| 42% | PETRAEUS | 8 | David ___, C.I.A. director under Obama |
| 41% | AVADUVERNAY | 11 | "Selma" director who was the first African-American woman nominated for a Best Picture Oscar (2 wds.) |
| 40% | KANYEWEST | 9 | About whom Obama said "He is a jackass. But he's talented" |
| 40% | TARZAN | 6 | One who might say "Well, I'll be a monkey's uncle!"? |
| 39% | GHOST | 5 | ___ Rider, Latin American Marvel superhero who is a character in "Agents of S.H.I.E.L.D." |
| 39% | JACKIESTILES | 12 | 2016 Women's Basketball Hall of Fame inductee who was the first Division I player to score over 1,000 points in a season: 2 wds. |
| 39% | TEBOW | 5 | Tim who was the first sophomore to win a Heisman |
| 39% | LYRIC | 5 | "In the town where I was born / Lived a man who sailed to sea" is the first one in "Yellow Submarine," by the Beatles |
| 39% | SALONGA | 7 | Lea who was the first Asian actress to win a Tony |
| 39% | LORRE | 5 | Peter who was the first actor to play a Bond villain |
| 39% | IRA | 3 | Songwriter Gershwin who was the first lyricist to win a Pulitzer |
| 38% | MOROCCA | 7 | Former "Daily Show" correspondent who is a regular panelist on NPR's "Wait Wait... Don't Tell Me!": 2 wds. |
| 38% | OTTAWAS | 7 | First Nations people for whom a city is named |
| 38% | TOASTER | 7 | I prepare your morning's first bite. I turn bread into a golden delight. Who am I? |
| 38% | ELLEN | 5 | Broidy who was a co-organizer of the first gay pride march |
| 38% | MATAHARI | 8 | Dancer who was a German spy during World War I: 2 wds. |
| 38% | OPTIMIST | 8 | I'm after new top first, being a cheerful type |