| 100% | ODOM | 4 | Leslie ___ Jr. (actor who plays Dr. Arbuthnot in 2017's "Murder on the Orient Express") |
| 73% | KENNETHBRANAGH | 14 | Actor who played Hercule Poirot in 2017's "Murder on the Orient Express" and 2022's "Death on the Nile": 2 wds. |
| 73% | KENNETH | 7 | Actor Branagh who plays Hercule Poirot in 2017's "Murder on the Orient Express" |
| 60% | LESLIEODOMJR | 12 | "Murder on the Orient Express" actor who played Aaron Burr in "Hamilton": 3 wds. |
| 59% | JOHNNYDEPP | 10 | "Murder on the Orient Express" actor who plays retired detective Russell Poole in 47-Across (2 wds.) |
| 56% | ODOM | 4 | "Murder on the Orient Express" actor Leslie ___, Jr. |
| 56% | ODOM | 4 | "Murder on the Orient Express" actor Leslie ___ Jr. |
| 54% | KENNETHBRANAGH | 14 | "Murder on the Orient Express" (2017) star who is the only actor to direct himself playing Hercule Poirot (2 wds.) |
| 54% | ALBERTFINNEY | 12 | Actor who played Hercule Poirot in the 1974 film "Murder on the Orient Express": 2 wds. |
| 53% | PENELOPECRUZ | 12 | "Murder on the Orient Express" actress who plays Laura Ferrari in "Ferrari" (2 wds.) |
| 50% | KENNETHBRANAGH | 14 | "Murder on the Orient Express" and 45-Across star who is the only actor to direct himself playing Hercule Poirot (2 wds.) |
| 50% | ALBERTFINNEY | 12 | "Murder on the Orient Express" (1974) star who is the only actor to be nominated for an Oscar for playing Hercule Poirot (2 wds.) |
| 49% | LESLIE | 6 | __ Odom Jr. Murder On the Orient Express Arbuthnot |
| 48% | MATT | 4 | ___ Damon, actor who plays Leslie Groves Jr. in the 2023 film "Oppenheimer" |
| 48% | JESSEWILLIAMS | 13 | "Grey's Anatomy" actor who plays a camera operator on "Only Murders in the Building" (2 wds.) |
| 47% | AMYRYAN | 7 | Actor who played Holly on The Office and Jan on Only Murders in the Building |
| 47% | STEVEMARTIN | 11 | "Dirty Rotten Scoundrels" actor who plays Charles on "Only Murders in the Building" (2 wds.) |
| 46% | GARYSINISE | 10 | Actor who played Mac Taylor on "CSI: NY" and was awarded the James Cardinal Gibbons Medal in 2017 |
| 46% | ALBERTFINNEY | 12 | "Annie" actor who played Belgian detective Hercule Poirot in the 1974 film "Murder on the Orient Express": 2 wds. |
| 46% | DEPP | 4 | "Murder on the Orient Express" (2017) actor |
| 45% | PAUL | 4 | With 50-Across, "Ant-Man" actor who plays a murdered Hollywood actor on "Only Murders in the Building" |
| 45% | DEREK | 5 | "Murder on the Orient Express" (2017) actor Jacobi |
| 45% | DENHOLM | 7 | ___ Elliott, actor who played Dr. Marcus Brody in Steven Spielberg's "Raiders of the Lost Ark" |
| 44% | MARTINFREEMAN | 13 | "The Hobbit" actor who plays Dr. Watson on the BBC's "Sherlock": 2 wds. |
| 44% | DAISY | 5 | Actress Ridley of 2017's "Murder on the Orient Express" |
| 44% | INGRIDBERGMAN | 13 | "Casablanca" actress who played a Swedish missionary in "Murder on the Orient Express": 2 wds. |
| 44% | CILLIANMURPHY | 13 | "Inception" actor who plays the Shivering Soldier in 2017's "Dunkirk" (2 wds.) |
| 43% | KENJEONG | 8 | Actor who played Leslie Chow in The Hangover |
| 43% | KYLECHANDLER | 12 | Actor who plays Cathcart in the Hulu miniseries based on 39-Across's "Catch-22" (2 wds.) |
| 43% | DAVIDOYELOWO | 12 | “Interstellar” actor who played Dr. Martin Luther King Jr. in “Selma” |