| 100% | SOLEDDOWNTHERIVER | 17 | Like shoes made in St. Louis and finished in New Orleans? |
| 47% | UPRIVER | 7 | Like St. Louis vis-à-vis New Orleans |
| 46% | CATCAFES | 8 | Eateries like Mauhaus in St. Louis and Pounce in Charleston |
| 39% | STS | 3 | Desire and Bourbon in New Orleans, e.g.: Abbr. |
| 39% | STS | 3 | Bourbon and Magazine, in New Orleans (Abbr.) |
| 38% | TABOO | 5 | Like eating pizza with a fork and knife in New York City |
| 38% | AVE | 3 | St. Bernard in New Orleans, e.g.: Abbr. |
| 37% | NCIS | 4 | Franchise with locations in New Orleans and L.A. |
| 36% | MUGGY | 5 | Like St. Louis in August |
| 36% | NCIS | 4 | It has spinoffs set in New Orleans and Los Angeles |
| 36% | LOUISARMSTRONG | 14 | Jazz trumpeter and singer born in New Orleans: 2 wds. |
| 36% | FROG | 4 | "The Princess and the ___" (Disney movie set in New Orleans) |
| 36% | BOURBON | 7 | A night street in New Orleans and a drink's name |
| 36% | NCIS | 4 | TV drama with spinoffs set in Los Angeles and New Orleans |
| 36% | HARRYCONNICKJR | 14 | Pop and jazz singer born in New Orleans: 3 wds., abbr. |
| 35% | NCIS | 4 | Drama with spinoffs set in L.A. and New Orleans |
| 35% | ALONE | 5 | Like Lindbergh in the Spirit of St. Louis |
| 35% | ELI | 3 | 2019 horror film shot in New Orleans and released October 18 by Netflix |
| 35% | NCIS | 4 | CBS police show with spinoffs in L.A. and New Orleans |
| 34% | YOURHONOR | 9 | Showtime miniseries set in New Orleans starring 15-Across and 33-Across (2 wds.) |
| 34% | ONEMOTIME | 9 | 2:00 in New York vis-à-vis St. Louis? |
| 34% | NCIS | 4 | Series with spinoffs set in Los Angeles and New Orleans |
| 34% | NCIS | 4 | TV drama with spinoffs set in Hawaii and New Orleans |
| 34% | JAZZ | 4 | Music genre for Louis Armstrong, which originated in New Orleans, Louisiana, in the late 1800s |
| 34% | AUTUMN | 6 | Ella Fitzgerald and Louis Armstrong's fall song "___ in New York" |
| 33% | MEMORIALDAY | 11 | Regular observance in Bangor, St. Louis, Providence and Mobile? |
| 33% | HURRICANE | 9 | Rum and passion-fruit syrup cocktail associated with Pat O'Brien's Bar in New Orleans |
| 33% | DISBARRED | 9 | Forbidden from practicing law, like Rudy Giuliani in New York and D.C. (July and September, 2024) |
| 32% | MESAS | 5 | Plateaus found in states like Colorado and New Mexico |
| 32% | KITT | 4 | Eartha —, singer and actress who played Gogo Germaine in 1958 biopic St Louis Blues |