| 100% | SCIATIC | 7 | Long nerve running down the back of the leg |
| 53% | SCIATIC | 7 | ___ nerve (nerve that runs the length of a leg) |
| 51% | SCIATIC | 7 | Kind of nerve that runs through the leg |
| 49% | RETINA | 6 | Nerve layer in the back of the eye |
| 48% | DATELINE | 8 | It runs down the middle of the Pacific |
| 48% | CALVES | 6 | The backs of the lower legs |
| 46% | SCIATIC | 7 | — nerve, that part of the nervous system beginning in the lower back and extending down the thigh |
| 46% | CALF | 4 | Back of the lower leg |
| 46% | HAMSTRING | 9 | Long tendon at the back of the thigh and knee |
| 46% | HAMMY | 5 | Muscle on the back of your leg, slangily |
| 45% | RETINAL | 7 | Related to nerves in the back of the eye |
| 45% | INSEAM | 6 | It runs down the leg |
| 44% | THIGHBONE | 9 | Longest skeletal part of the leg (not technical) |
| 44% | COATTAIL | 8 | Long flap at the back of a jacket |
| 43% | SILLITOE | 8 | Wrote The Loneliness of the Long-Distance Runner |
| 43% | CALF | 4 | Back part of the lower leg |
| 42% | ENO | 3 | Running back ___ Benjamin of the Arizona Cardinals |
| 42% | RATTAIL | 7 | 1980s short hair with a long strand down the back |
| 42% | TIBIAL | 6 | ___ nerve (branch of the sciatic nerve in the leg) |
| 42% | SCIATICA | 8 | Back pain involving the body's longest nerve |
| 42% | HITCHKICK | 9 | Long jump technique of running "in the air" |
| 41% | TRAY | 4 | Item that drops down from the back of an airplane seat |
| 41% | MARKER | 6 | Back __, traveller at the end of a running group |
| 41% | EROSION | 7 | Long-term result of a run on the bank? |
| 39% | OPERA | 5 | The Phantom of the __, long-running stage musical |
| 39% | FALLINGLEAVES | 13 | Autumn occurrence, and a hint to the start of the other four longest Down answers |
| 39% | EARL | 4 | ___ Campbell, former NFL running back of the Houston Oilers who retired at the age of 31 |
| 39% | BARRY | 5 | ___ Sanders, former NFL running back of the Detroit Lions who retired at the age of 31 |
| 39% | BASSES | 6 | The back of the choir? |
| 39% | NAPE | 4 | The back of the neck |