| 100% | METS | 4 | M.L.B. team that was the first to trade a player for himself (Harry Chiti in 1962) |
| 41% | LISALESLIE | 10 | L.A. Sparks player who was the first to dunk in a W.N.B.A. game |
| 39% | PALM | 4 | Co. that was the first to successfully market a PDA worldwide in 1997 |
| 38% | MARLINS | 7 | Florida squad that was the first to win two World Series titles as a wild-card team |
| 37% | NETS | 4 | N.B.A. team that recently agreed to its first trade with the Knicks in over 40 years |
| 36% | ALABAMA | 7 | Montgomery's state that was the first US state to recognize Christmas as a holiday in 1836 |
| 36% | IKEA | 4 | Furniture store that was the first company to show a gay couple in an American TV commercial |
| 36% | ASTRO | 5 | Member of the M.L.B. team whose manager and G.M. were suspended and dismissed in January, 2020, due to a sign-stealing scandal |
| 36% | IKEA | 4 | Company that was the first in the U.S. to air a TV ad with a gay couple (1994) |
| 36% | SUTTERSMALL | 11 | Historic shopping center that was the first to be called "a gold mine for investors"? |
| 35% | ANGELA | 6 | Bassett who was the first person to be nominated for an Oscar for acting in a Marvel movie |
| 35% | LISALESLIE | 10 | Basketball Hall of Fame inductee who was the first player to dunk in a WNBA game: 2 wds. |
| 34% | HELEN | 5 | I was the first deaf-blind person to earn a B.A. degree and I campaigned for women's rights |
| 34% | SHALOMMEIRTOWER | 15 | Tel Aviv skyscraper that was the first to be built in the Mideast |
| 33% | TMZ | 3 | Hollywood website that was the first to report Michael Jackson's death in 2009 |
| 33% | MARINER | 7 | Member of the only M.L.B. team never to have played in a World Series |
| 33% | SWOOPES | 7 | Sheryl who was the first W.N.B.A. player to have a signature shoe |
| 33% | REDDAWN | 7 | 1984 Patrick Swayze film that was the first to be released with a PG-13 rating |
| 33% | ENDZONE | 7 | In American football, the area behind the goals that a ball must cross for a touchdown to be awarded |
| 32% | JACKIESTILES | 12 | 2016 Women's Basketball Hall of Fame inductee who was the first Division I player to score over 1,000 points in a season: 2 wds. |
| 32% | OBERLIN | 7 | Ohio college that was the first in the U.S. to admit women |
| 32% | ERNANI | 6 | Verdi work that was the first opera to be recorded in its entirety |
| 32% | ENDZONE | 7 | Area behind the goals in American football that a ball must cross for a touchdown to be awarded |
| 32% | ADRIATIC | 8 | RMS ___, British ship that was the first ocean liner to feature a swimming pool |
| 32% | EDITHWHARTON | 12 | 13-Across and 25-Across writer who was the first woman to win a Pulitzer Prize in Literature, for her 1920 novel "The Age of Innocence" (2 wds.) |
| 32% | BAD | 3 | "___ was the blood of the song in the cab / On your first trip to L.A." |
| 32% | OBERLIN | 7 | Ohio college that was the first in the U.S. to award degrees to women |
| 32% | PEPSI | 5 | Soda that was the first American brand to be sold widely in the Soviet Union |
| 32% | ICHIROSUZUKI | 12 | First M.L.B. player to enter the Meikyukai (a Japanese baseball hall of fame) |
| 32% | NODOFF | 6 | At midnight when I'm still writing clues for the puzzle that absolutely has to be in Florida by 8:00 am, I have a tendency to do this |