| 100% | SETH | 4 | Macfarlane who cites Rex Harrison as the inspiration for Stewie's voice on "Family Guy" |
| 31% | SAMROCKWELL | 11 | "The Best of Enemies" actor who is the voice of Vic Reynolds on "F Is for Family" (2 wds.) |
| 29% | ALEXBORSTEIN | 12 | "Family Guy" voice actress who plays Midge's manager Susie Myerson on "The Marvelous Mrs. Maisel" (2 wds.) |
| 28% | HANKAZARIA | 10 | "The Simpsons" voice actor who won an Emmy for his guest role as Ed Cochran on 43-Across: 2 wds. |
| 28% | DERN | 4 | Actress Laura who voices Sue Murphy on "F Is for Family" |
| 27% | SETH | 4 | "Family Guy" creator and Oscars host MacFarlane who was the roast master for 28-Across and 42-Across |
| 26% | MEG | 3 | Stewie's sister on "Family Guy" |
| 26% | ROBREINER | 9 | "All in the Family" costar who guest-starred as himself on "The Simpsons": 2 wds. |
| 26% | SETHGREEN | 9 | Actor who provides the voice of Chris Griffin on "Family Guy" |
| 26% | LAPTOP | 6 | Computer for one who's on the go |
| 26% | NASH | 4 | Clarence ___, actor who voiced Donald Duck and went on to voice the dog barks for "101 Dalmatians" |
| 26% | NIALLHORAN | 10 | One Direction singer who's in his second season as a coach on "The Voice": 2 wds. |
| 26% | BELL | 4 | Joseph ___, surgeon whom Arthur Conan Doyle cites as inspiration for the character of Sherlock Holmes |
| 25% | KELLYCLARKSON | 13 | "Miss Independent" singer who has been a coach on "The Voice" for the last five seasons (2 wds.) |
| 25% | REBAMCENTIRE | 12 | Red-haired country singer who's in her first season as a coach on "The Voice": 2 wds. |
| 25% | SETH | 4 | MacFarlane who created TV's "Family Guy" |
| 25% | MILAKUNIS | 9 | That '70s Show star who voices Meg on Family Guy |
| 25% | JONAS | 5 | Singer Nick who served as a judge on “The Voice” |
| 25% | GRETAGARBO | 10 | Actress who's the inspiration for this puzzle's theme? |
| 25% | BRIAN | 5 | Cox who plays the family patriarch on HBO's "Succession" |
| 25% | PROTEM | 6 | One who's acting as boss for the moment: President ___ |
| 25% | INTERN | 6 | College student who's on staff for the summer, maybe |
| 25% | LOIS | 4 | Stewie's mother, on "Family Guy" |
| 25% | SARA | 4 | Ramirez who voiced Queen Miranda on Disney's "Sofia the First" |
| 25% | JOHNLEGEND | 10 | "All of Me" singer who's back, along with Gwen Stefani, as a veteran coach on "The Voice": 2 wds. |
| 25% | ARCH | 4 | Edith's husband on "All in the Family," for short |
| 25% | ADAMWEST | 8 | Family Guy mayor, or the actor providing his voice |
| 25% | ABE | 3 | Lincoln who's depicted on the penny, for short |
| 25% | PET | 3 | Brian the dog on "Family Guy," for instance |
| 24% | ADAM | 4 | Singer Levine who returned as a coach on "The Voice" in 2025 |