| 100% | CLAUDIUS | 8 | Main antagonist in Hamlet: King __ |
| 68% | SCAR | 4 | Main antagonist in "The Lion King" who is Mufasa's younger brother |
| 62% | JACK | 4 | ___ Torrance, main antagonist in Stephen King's novel "The Shining" |
| 58% | SID | 3 | Main antagonist in "Toy Story" |
| 57% | HADES | 5 | Main antagonist in Disney's "Hercules" |
| 57% | IAGO | 4 | Main antagonist in Shakespeare's "Othello" |
| 57% | MANDARK | 7 | Main antagonist in Dexter's Laboratory |
| 56% | VOLDEMORT | 9 | Main antagonist in the Harry Potter series |
| 56% | OBRIEN | 6 | Main antagonist in George Orwell's "1984" |
| 54% | GARGAMEL | 8 | Main antagonist in Peyo's comic strip The Smurfs |
| 54% | RED | 3 | ___ Queen, main antagonist in "Alice in Wonderland" |
| 53% | ROTH | 4 | Hyman ___, main antagonist in "The Godfather Part II" |
| 53% | LORD | 4 | ___ Voldemort, main antagonist in the "Harry Potter" series |
| 52% | BATES | 5 | Norman ___, the main antagonist in the famed horror film "Psycho" |
| 51% | HADES | 5 | Main antagonist in "Hercules" who is the fast-talking God of the Underworld |
| 50% | ROSS | 4 | Edgar ___, federal agent who is the main antagonist in "Red Dead Redemption" |
| 49% | SHAN | 4 | ___ Yu, main antagonist in "Mulan" who is the cruel leader of the Huns |
| 49% | VIL | 3 | Cruella de ___, main antagonist in "101 Dalmations" who kidnaps puppies for their fur |
| 49% | GOTHEL | 6 | Mother___, main antagonist in "Tangled" who kidnaps and keeps Rapunzel hostage for years |
| 48% | RED | 3 | ___ Queen, main antagonist in "Alice in Wonderland" who is the bloodthirsty ruler of Wonderland |
| 47% | GANON | 5 | Demonic boar-like creature who is the main antagonist in "The Legend of Zelda" series |
| 46% | SCAR | 4 | Antagonist for Simba and Mufasa in "The Lion King" |
| 46% | SHERE | 5 | ___ Khan, main antagonist in "The Jungle Book" who is feared by the inhabitants of the jungle |
| 46% | GLADOS | 6 | Artificial intelligence computer system which is the main antagonist in the "Portal" video game series: Abbr. |
| 45% | CLAUDIUS | 8 | Murderer of King Hamlet in Shakespeare's play |
| 45% | GANON | 5 | Monstrous boar-like creature who is the main antagonist in "The Legend of Zelda" video game series |
| 44% | MOUSE | 5 | The ___ King, antagonist who leads a rodent army in 11a |
| 40% | TORRANCE | 8 | Jack __, main character in S. King's The Shining |
| 40% | WHITE | 5 | Carrie ___, main villain in Stephen King's novel "Carrie" |
| 39% | HEEL | 4 | Antagonist in pro wrestling |