| 100% | SPERMWHALE | 10 | Mammal with the largest brain of any animal |
| 70% | MANTA | 5 | Ray with the largest brain of any fish |
| 63% | OSTRICH | 7 | Bird with the largest eggs of any land animal |
| 51% | OSTRICH | 7 | Bird that lays the largest egg of any animal |
| 49% | ORCA | 4 | Animal whose brain has the most gray matter of any mammal |
| 47% | MANTARAY | 8 | Fish with the largest brain |
| 46% | OSTRICH | 7 | Flightless bird that lays the largest eggs of any land animal |
| 45% | MAKO | 4 | Shark species with the largest brain-to-body ratio |
| 44% | ARMADILLO | 9 | Burrowing animal with a coat of "armor," that is the official state small mammal of Texas |
| 43% | SEA | 3 | With 6-Across, it has the densest fur of any animal |
| 43% | CEREBRUM | 8 | The largest part of the brain |
| 42% | BLUEWHALE | 9 | The largest mammal of all sea creatures |
| 42% | EASE | 4 | With the greatest of ___ (without any trouble) |
| 42% | INDIA | 5 | Country with the largest population of vegetarians |
| 42% | CEREBRUM | 8 | The largest and uppermost part of the brain |
| 42% | SEAOTTER | 8 | It has the densest fur of any animal |
| 42% | INDONESIA | 9 | Country with the largest number of active volcanos |
| 42% | PERU | 4 | Country with the largest number of Quechua speakers |
| 41% | CEREBRUM | 8 | Largest part of the brain |
| 41% | CEREBRUM | 8 | Large part of the brain |
| 40% | CEREBRUM | 8 | Large, front part of the brain |
| 40% | APE | 3 | Large, tailless mammal of the jungle |
| 40% | ELKS | 4 | Large, antlered animals of the Rockies |
| 40% | CEREBRUM | 8 | Largest, most complex part of the brain |
| 40% | TAIWAN | 6 | Asian island with the largest economy that's not part of the United Nations |
| 39% | LION | 4 | Large animal that's the mascot of MGM |
| 39% | ANAT | 4 | Subject dealing with the structure of humans and animals, for short |
| 39% | SEA | 3 | With 47-Across, marine animal of the class Asteroidea |
| 39% | TEMPORALLOBE | 12 | Part of the brain associated with memory |
| 39% | AMYGDALA | 8 | Region of the brain associated with emotions |