| 100% | MURSE | 5 | Man bag, in early-two-thousands slang |
| 61% | PIMPED | 6 | Souped up, as one’s ride, in early-two-thousands slang |
| 49% | SARS | 4 | Outbreak in early-two-thousands news |
| 46% | GEES | 4 | Thousands, in slang |
| 45% | MILKTRAIN | 9 | Early morning transport, in British slang |
| 45% | CHEESEBUS | 9 | Early morning transport, in American slang |
| 45% | GEES | 4 | Thousands, in heist slang |
| 45% | GEE | 3 | Thousand dollars, in slang |
| 44% | GEES | 4 | Thousands of dollars, in slang |
| 44% | FRIEDEGGS | 9 | "Flop two," in diner slang |
| 43% | BAIL | 4 | Exit early, in slang |
| 43% | NASCARDADS | 10 | Largely white and rural set of voters, in early-two-thousands political analysis |
| 42% | ODARKTHIRTY | 11 | Very early morning, in slang |
| 42% | HOSERS | 6 | Con men, in slang |
| 42% | DADDY | 5 | Attractive older man, in gay slang |
| 42% | FRIENDOFDOROTHY | 15 | Gay man, in gay slang |
| 41% | ELI | 3 | Manning who was the MVP in two Super Bowls |
| 40% | SARS | 4 | Disease in an early-two-thousands outbreak, familiarly |
| 40% | OGS | 3 | Macho men, in hip-hop slang: Abbr. |
| 40% | TECHBUBBLE | 10 | It burst in the early two-thousands and sent dot-com stocks tumbling |
| 39% | BLEEDER | 7 | Grounder that squeezes between two infielders, in baseball slang |
| 39% | SNAKEEYES | 9 | Dice roll of two ones, in slang: 2 wds. |
| 39% | OTTER | 5 | Slender, hairy man, in gay slang |
| 39% | OWLS | 4 | Two residents of the Old Man's beard, in a Lear verse |
| 38% | TANTRA | 6 | Hindu tradition that's two men's names in reverse |
| 38% | HARPER | 6 | Surname of the brothers in Two and a Half Men |
| 38% | AFTERSHAVE | 10 | Item in a man bag, perhaps |
| 38% | ELI | 3 | Two-time Super Bowl MVP quarterback Manning who announced his retirement in 2020 |
| 38% | LSEVEN | 6 | Square, in 1950s slang, indicated visually by a two-hand gesture |
| 38% | NONO | 4 | One of two pitching gems by 28-Across, in slang (Hyph.) |