| 100% | YEAR | 4 | Margaret Atwood's "The ___ of the Flood" |
| 89% | YEAR | 4 | Margaret Atwood novel "The___ of the Flood" |
| 64% | TALE | 4 | "The Handmaid's ___," Margaret Atwood's 1985 dystopian novel that follows the journey of a woman in a totalitarian state |
| 62% | HANDMAIDS | 9 | "The ___ Tale", Hulu's dystopian drama web television, based on a novel of the same name by Margaret Atwood |
| 60% | CLAIREDANES | 11 | "Homeland" actress who narrates an audiobook of Margaret Atwood's "The Handmaid's Tale": 2 wds. |
| 58% | HANDMAIDSTALE | 13 | With "The," Hulu drama that featured a cameo by Margaret Atwood, author of the source material: 2 wds. |
| 57% | BRUCEMILLER | 11 | Creator of the Hulu TV series "The Handmaid's Tale," based on the 1985 novel of the same name by Margaret Atwood: 2 wds. |
| 57% | OTTAWAN | 7 | The Handmaid's Tale's Margaret Atwood, for one |
| 55% | MORAL | 5 | "___ Disorder," 2006 collection of connected short stories by Margaret Atwood which chronicles the pains of a Canadian family |
| 54% | HOTLIPS | 7 | Nickname of the “M*A*S*H” character Margaret Houlihan |
| 52% | ATWOOD | 6 | Margaret, author of The Testaments |
| 51% | BURBIDGE | 8 | Margaret __, director of the Greenwich Observatory |
| 51% | ARG | 3 | S. Amer. home of the tango |
| 51% | MANVILLE | 8 | Lesley __ plays Margaret in season 6 of The Crown |
| 51% | ATWOOD | 6 | Margaret __, author of the sequel The Testaments |
| 50% | OLEMISS | 7 | The Rebels of the S.E.C. |
| 50% | LSU | 3 | The Tigers of the S.E.C. |
| 50% | UGA | 3 | The Bulldogs of the S.E.C. |
| 50% | POORS | 5 | The "P" of the S&P 500 |
| 50% | POORS | 5 | The “P” of the S. & P. 500 |
| 50% | LLAMA | 5 | S. American mammal of the camel family |
| 50% | DRABBLE | 7 | Margaret, author of The Millstone, The Red Queen |
| 50% | MTOSSA | 6 | It's S. of the Vale of Tempe |
| 49% | STEARNS | 7 | The S. of T.S. Eliot |
| 49% | LSU | 3 | Tigers of the S.E.C. |
| 49% | SPAMS | 5 | Floods the inbox of |
| 49% | SPORT | 5 | The S of SUV |
| 49% | STD | 3 | The S of EST |
| 49% | SIL | 3 | The S of RSVP |
| 49% | SIGN | 4 | The S of ASL |