| 100% | LUIGI | 5 | Mario's younger and taller fraternal twin brother who is the protagonist of the video game "Mario is Missing!" |
| 48% | LUIGI | 5 | Plumber character who is Mario's twin brother and sidekick in the video game franchise |
| 38% | EDW | 3 | Prince who's the younger brother of Chas. and who is uncle to Wm. |
| 38% | MADDEN | 6 | Benji and Joel ___, twin brothers who are part of the rock band Good Charlotte |
| 36% | MEGA | 4 | ___ Man, animated protagonist of the eponymous video game franchise who is also known as Rockman |
| 35% | BLU | 3 | Fictional macaw who is the protagonist of the "Rio" franchise and is named after his color |
| 35% | WARIO | 5 | Video-game antagonist whose name is a portmanteau of the protagonist's name and the Japanese word for "bad" |
| 34% | DAVIES | 6 | Ray and Dave ___, brothers who are a part of the band, The Kinks |
| 34% | MOE | 3 | Stooge who was the brother of Curly and Shemp |
| 33% | AISHATYLER | 10 | "Whose Line Is It Anyway?" host who voices characters in the video games "Halo: Reach," "Gears of War 3," and "Watch Dogs" (2 wds.) |
| 33% | TIGERWOODS | 10 | Golf superstar who was the face of the "PGA Tour" video game series until 2013: 2 wds. |
| 32% | BEETLEBAILEY | 12 | Soldier who is the brother of Lois Flagston of "Hi and Lois" (2 wds.) |
| 32% | WIZARD | 6 | Fraud who is the target of Dorothy Gale's quest in the land of Oz, and the supposed protagonist in the namesake films |
| 32% | YOSHI | 5 | Fictional dinosaur who is Mario's sidekick and has his own spin-off video game series |
| 32% | TOAD | 4 | Mushroom-like humanoid who is Princess Peach's attendant and is the protagonist of "Wario's Woods" |
| 31% | SEBASTIAN | 9 | Shakespearean character who is the brother of Viola in "Twelfth Night" and who settled in the region of Illyria |
| 31% | ELIZABETH | 9 | ___ Bennet, the protagonist of "Pride and Prejudice," who is one of the most-loved fictional female characters |
| 31% | ELI | 3 | Brother of 30-Across who was the 2008 and 2012 Super Bowl MVP as a Giants quarterback |
| 31% | ALEX | 4 | ___ Cross, fictional former FBI agent and psychologist created by James Patterson who is the protagonist in many of his books |
| 31% | TURING | 6 | Mathematician who was the subject of "The Imitation Game" |
| 31% | LUIGI | 5 | Mario's younger brother, in video games |
| 31% | WADE | 4 | Alma ___, psychic who is the main antagonist of the "F.E.A.R." video game series |
| 30% | HUCKLEBERRY | 11 | ___ Finn, a fictional character who first appeared in 51a and is a friend of the protagonist |
| 30% | IRENE | 5 | Adler who is the protagonist of the novel “Good Night, Mr. Holmes” |
| 30% | ALAN | 4 | Mathematician Turing who was the subject of "The Imitation Game" |
| 30% | BENJEN | 6 | ___ Stark, Ned Stark's brother who was part of the Night's Watch in "Game of Thrones" |
| 30% | GANON | 5 | Monstrous boar-like creature who is the main antagonist in "The Legend of Zelda" video game series |
| 30% | VINDIESEL | 9 | "The Fate of the Furious" actor who has a fraternal twin brother named Paul: 2 wds. |
| 30% | ALAN | 4 | Computer scientist Turing who was the subject of "The Imitation Game" |
| 30% | DRAKE | 5 | Nathan ___, animated protagonist of the video game franchise "Uncharted" |