| 100% | CATALEPSY | 9 | Medical condition characterised by muscular rigidity and a loss of sensation |
| 37% | EPILEPSY | 8 | Medical disorder characterised by the periodic sudden loss of consciousness |
| 35% | AMNESIA | 7 | A condition typified by a loss of memory |
| 34% | VERTIGO | 7 | A spinning sensation and loss of balance |
| 32% | GRANDMAL | 8 | Form of epilepsy characterised by loss of consciousness and violent convulsions |
| 30% | OBESITY | 7 | Medical condition seen by the excess of body fat |
| 30% | WRINKLEFREE | 11 | Like a shirt condition suggested by the ends of 16-, 27- and 46-Across |
| 29% | TYPHUS | 6 | Infectious bacterial disease characterised by headaches and a fever |
| 29% | DORIC | 5 | Classical order of architecture characterised by a column with no base and a heavy fluted shaft |
| 29% | DISORDER | 8 | A state of confusion; and abnormal condition |
| 29% | TWIST | 5 | 1960s dance characterised by gyrations of the arms and hips |
| 28% | HECTOR | 6 | A Trojan and son of Priam; killed by Achilles |
| 28% | MEASLES | 7 | Highly contagious viral disease characterised by a rash of small red spots |
| 28% | VARICOSE | 8 | Affected by a condition of swollen blue leg veins |
| 28% | WORKISTHERUINOF | 15 | Start of a quote by 26- and 32-Down |
| 28% | CRUMB | 5 | Part of a path left by Hansel and Gretel |
| 28% | MYOUTPUTISDOWNBUT | 17 | Start of a comment by 3- and 126-Down |
| 27% | DOCTRINE | 8 | Set of beliefs held and taught by a certain group |
| 27% | LETITBE | 7 | The name of a song and album by the Beatles |
| 27% | PRINTS | 6 | Works of art made by a raised surface and inking |
| 27% | VERTIGO | 7 | Dizzying sensation, a medical condition |
| 27% | DNASTRAND | 9 | Half of a double helix polymer discovered by Watson and Crick |
| 27% | BOW | 3 | "Take a ___" (title of #1 hits by Madonna and Rihanna) |
| 27% | ANEMIA | 6 | Blood condition caused by a lack of red cells |
| 26% | SLEET | 5 | A kind of weather condition where ice pellets are mixed with rain and snow |
| 26% | WHATISLOVE | 10 | 1993 dance hit, and a musical question answered by the starts of 18-, 29-, and 48-Across? |
| 26% | FLIPFLOPPING | 12 | Switching positions, and a phrase spelled by the first letters of 12 words that have switched positions |
| 26% | MEN | 3 | Of Mice and ___, "Restoring Force" band whose name is inspired by a John Steinbeck novel |
| 26% | DIARY | 5 | "___ of a Mad Black Woman," 2005 rom-com written by and starring Tyler Perry |
| 26% | CROCHET | 7 | Piece of needlework made by looping and intertwining thread with a hooked needle |