| 100% | MARCUSWELBYMD | 13 | Medical drama starring 18-Across and 40-Across that debuted in September 1969 (3 wds.) |
| 59% | MEDICALCENTER | 13 | Hospital drama starring James Daly and Chad Everett that debuted in 1969 (2 wds.) |
| 54% | THEBRADYBUNCH | 13 | Family sitcom starring Robert Reed and Florence Henderson that debuted in 1969 (3 wds.) |
| 52% | THEWESTWING | 11 | A political drama that debuted in the 90s, starring the likes of Rob Lowe and Martin Sheen: 3 wds. |
| 51% | THENOTEBOOK | 11 | 2004 romantic drama starring 18-Across and 32-Across that was adapted as a Broadway musical in 2024 (2 wds.) |
| 48% | ALLINTHEFAMILY | 14 | Norman Lear sitcom starring 16-Across and 35-Across that debuted in January 1971 (4 wds.) |
| 48% | THEGODFATHER | 12 | Oscar-winning film starring 14-Across and 28-Across that debuted in March 1972 (2 wds.) |
| 48% | ANIMALKINGDOM | 13 | TNT family crime drama starring 18-Across and 40-Across (2 wds.) |
| 45% | THEJEFFERSONS | 13 | Sitcom starring Sherman Hemsley and 15-Across that debuted January 18, 1975 (2 wds.) |
| 45% | SPINCITY | 8 | Political sitcom starring Barry Bostwick, 15-Across, 20-Across, and 37-Across that debuted in 1996 (2 wds.) |
| 45% | THEPRACTICE | 11 | Legal drama starring Dylan McDermott that debuted in 1997 and ran for eight seasons (2 wds.) |
| 44% | JUSTSHOOTME | 11 | Sitcom starring David Spade that debuted in 1997 and ran for seven seasons (3 wds.) |
| 43% | THEODDCOUPLE | 12 | 1970s Neil Simon sitcom starring 17-Across and 41-Across that debuted 50 years ago (3 wds.) |
| 43% | EBONYANDIVORY | 13 | 1982 Stevie Wonder/Paul McCartney song that also describes 18- and 40-Across: 3 wds. |
| 43% | PLAYMISTYFORME | 14 | 1971 thriller starring 18-Across and 41-Across, directed by 18-Across in his directorial debut (4 wds.) |
| 43% | LAFEMMENIKITA | 13 | Action series starring Peta Wilson that debuted in 1997 and ran for five seasons (3 wds.) |
| 43% | THEGOODDOCTOR | 13 | Medical drama starring 15-Across, 30-Across, and Freddie Highmore (3 wds.) |
| 43% | THEGILDEDAGE | 12 | HBO historical drama that features both 18- and 33-Across: 3 wds. |
| 43% | THEGOODFIGHT | 12 | Paramount+ legal drama that features both 18- and 33-Across: 3 wds. |
| 43% | SESAME | 6 | With 29-Across, children's show starring Big Bird and Oscar the Grouch that debuted in 1969 |
| 42% | THEPITT | 7 | HBO Max medical drama starring Noah Wyle and set in Pennsylvania: 2 wds. |
| 42% | THEBANDSVISIT | 13 | Broadway show by 40-Across starring 18-Across and Tony Shalhoub that won 10 2018 Tony Awards, including Best Musical (3 wds.) |
| 42% | SONSOFANARCHY | 13 | "Mayans M.C." precursor starring 15-Across as 30-Across that debuted in 2008 (3 wds.) |
| 42% | THERESIDENT | 11 | Medical drama starring 17-Across and 28-Across (2 wds.) |
| 42% | DOCTORODYSSEY | 13 | 2024-2025 medical drama aboard a cruise ship that starred 15-Across and Don Johnson: 2 wds. |
| 41% | THEBRADYBUNCH | 13 | Florence Henderson (1934-2016) played the mom on this show that debuted in 1969: 3 wds. |
| 41% | ITCHAPTERTWO | 12 | Horror sequel starring 18-Across and 32-Across set in Derry, Maine (3 wds.) |
| 41% | GAMEOFTHRONES | 13 | Drama that has featured Kit Harington and Rose Leslie, who married in 2018: 3 wds. |
| 40% | DOCTORODYSSEY | 13 | Drama that debuted in 2024 that stars Joshua Jackson as a cruise ship physician: 2 wds. |
| 40% | THERESIDENT | 11 | Fox TV medical drama starring 17-Across and 28-Across (2 wds.) |