| 100% | CHARLESDARWIN | 13 | Medical school dropout who wrote "On the Origin of Species": 2 wds. |
| 67% | GERTRUDESTEIN | 13 | Medical school dropout who wrote "The Autobiography of Alice B. Toklas": 2 wds. |
| 58% | CHARLESDARWIN | 13 | "On the Origin of Species" author who is buried at Westminster Abbey: 2 wds. |
| 52% | DARWIN | 6 | Charles __ wrote On the Origin of Species |
| 45% | CHARLESDARWIN | 13 | Biologist who gave the theory of evolution in "On the Origin of Species", that is depicted in the 2009 movie "Creation": 2 wds. |
| 44% | MARIOPUZO | 9 | Author who wrote the novel 15-Across was based on: 2 wds. |
| 43% | JONIMITCHELL | 12 | "Both Sides Now" singer-songwriter who wrote "Morning Glory on the Vine," a book of poetry and drawings (2 wds.) |
| 42% | GILLIANFLYNN | 12 | Author who wrote the film adaptation of her own "Gone Girl": 2 wds. |
| 42% | JAMES | 5 | With 35-Across, medical school dropout who wrote "Ulysses" |
| 42% | EVOLUTION | 9 | Theory in Darwin's On the Origin of Species |
| 42% | BETTYFORD | 9 | First Lady who wrote the 1978 memoir "The Times of My Life": 2 wds. |
| 41% | CHUCKBARRIS | 11 | TV program creator and host who wrote the memoir "Confessions of a Dangerous Mind": 2 wds. |
| 41% | STEPHENCHBOSKY | 14 | Author who wrote the film adaptation of his own "The Perks of Being a Wallflower": 2 wds. |
| 41% | RODERICKTHORP | 13 | Author who wrote "Nothing Lasts Forever," the novel on which movie in 17a was based: 2 wds. |
| 40% | DARWIN | 6 | Author of On The Origin of Species |
| 40% | KNOWNTO | 7 | On the radar of: 2 wds. |
| 40% | ASTO | 4 | On the subject of: 2 wds. |
| 40% | STEVEMARTIN | 11 | "The Pink Panther" actor who wrote the kids' book "Late for School": 2 wds. |
| 40% | MILEYCYRUS | 10 | "Wrecking Ball" singer who performs on the remix of 49-Across: 2 wds. |
| 40% | MURIELSPARK | 11 | Scottish author who wrote "The Prime of Miss Jean Brodie": 2 wds. |
| 40% | EMMALAZARUS | 11 | Female US poet who wrote "The New Colossus" (the poem on the Statue of Liberty): 2 wds. |
| 40% | CHOKEDUP | 8 | On the verge of tears: 2 wds. |
| 40% | SERENAWILLIAMS | 14 | 2003 and 2013 Best Female Athlete ESPY winner who wrote the kids' book "The Adventures of Qai Qai": 2 wds. |
| 39% | DARWIN | 6 | "On the Origin of Species" author |
| 39% | CHARLESDARWIN | 13 | "On the Origin of Species" author |
| 39% | DARWINISM | 9 | Fundamental theory of On the Origin of Species |
| 39% | DARWIN | 6 | "On the Origin of Species" author Charles |
| 39% | LUCRETIUS | 9 | Epicurean poet who wrote On the Nature of Things |
| 38% | JENNIFERGREY | 12 | "Dirty Dancing" actress who wrote the 2022 memoir "Out of the Corner" (2 wds.) |
| 38% | LENADUNHAM | 10 | "Girls" actress who wrote the memoir "Not That Kind of Girl": 2 wds. |