| 100% | OTC | 3 | Medicine that doesn't require prescriptions: Abbr. |
| 60% | OTC | 3 | Medicines that don't need a prescription: Abbr. |
| 52% | OTC | 3 | Like medications that don't require a prescription: Abbr. |
| 51% | OTC | 3 | Like drugs that don't require prescriptions (Abbr.) |
| 51% | PLACEBO | 7 | "Medicine" that doesn't actually contain medicine |
| 50% | FDA | 3 | Agency that regulates prescription medicine: Abbr. |
| 50% | HOMEBIRTH | 9 | Delivery that doesn’t require a driver |
| 50% | EASYA | 5 | Class that doesn’t require much effort |
| 50% | ORALEXAM | 8 | Test that doesn’t require a pencil |
| 50% | ANAEROBE | 8 | Organism that doesn't require oxygen |
| 50% | EASYA | 5 | Course that doesn't require cramming |
| 50% | LEGO | 4 | Brick that doesn't require mortar |
| 50% | NOD | 3 | Agreement that doesn't require speaking |
| 49% | EASYA | 5 | Class that doesn't require much studying |
| 49% | AUTO | 4 | Mode that doesn't require manual intervention |
| 49% | BOXEDWINE | 9 | Vino that doesn't require a corkscrew |
| 49% | ORAL | 4 | Exam that doesn't require a pen |
| 49% | ORAL | 4 | Exam that doesn't require a pencil |
| 48% | BETTA | 5 | Aquarium fish that doesn’t require an air pump |
| 48% | NOD | 3 | Auction bid that doesn’t require raising a paddle |
| 48% | WEBINAR | 7 | Class that doesn't require in-person attendance |
| 48% | ORAL | 4 | Exam that doesn't require pen or paper |
| 48% | PARTTIME | 8 | Job that doesn't require working full hours |
| 48% | DAYTRIP | 7 | Travel that doesn't require a hotel reservation |
| 48% | STOL | 4 | Abbr. for a plane that doesn't require much runway (but needs plenty of space if it goes backwards!) |
| 47% | EASYREAD | 8 | Book that doesn't require much time or thought |
| 47% | EASYA | 5 | Class that doesn't require much effort: 2 wds. |
| 47% | EASYA | 5 | Class that doesn't require a lot of studying |
| 47% | SUNTEA | 6 | Brewed beverage that doesn't require hot water |
| 47% | WAR | 3 | Card game that doesn't require any strategy |