| 100% | OTT | 3 | Mel who was the first NL player to surpass 500 home runs |
| 65% | OTT | 3 | Mel who was the first N.L.'er to hit 500 home runs |
| 53% | ALEXRODRIGUEZ | 13 | Former Yankees infielder who was the youngest player to hit 500 career home runs (2 wds.) |
| 49% | AARON | 5 | Yankee slugger Judge who was the first rookie to win the Home Run Derby |
| 48% | AROD | 4 | Former Yankee who was the youngest MLB player to hit 600 home runs |
| 48% | AROD | 4 | Former Yankee who was the youngest MLB player to hit 600 home runs, to fans |
| 47% | AROD | 4 | Former Yankee who was the youngest MLB player to hit 600 home runs, to fans (Hyph.) |
| 44% | MIKETROUT | 9 | Angels center fielder who was the youngest player to record 100 career home runs and 100 career stolen bases (2 wds.) |
| 43% | DIANA | 5 | Taurasi who was the first WNBA player to score more than 9,000 points |
| 42% | OTT | 3 | First N.L. player to hit 500 home runs |
| 42% | SWOOPES | 7 | Sheryl who was the first W.N.B.A. player to have a signature shoe |
| 41% | OTT | 3 | Mel, the first NLer to hit 500 homers |
| 41% | SOSA | 4 | Sammy who was the NL home run leader in 2000 and 2002 |
| 41% | SHERYLSWOOPES | 13 | Basketball Hall of Fame inductee who was the first player to sign with the WNBA: 2 wds. |
| 41% | RYUN | 4 | Jim ___, athlete who was the first high school junior to run a mile in under four minutes |
| 40% | LISALESLIE | 10 | Basketball Hall of Fame inductee who was the first player to dunk in a WNBA game: 2 wds. |
| 40% | AROD | 4 | Nickname of the slugger who was the youngest player to hit 600 home runs |
| 39% | OTT | 3 | First of the 49-Across to hit 500 home runs |
| 38% | LEADOFF | 7 | Be the first baseball player to bat: 2 wds. |
| 38% | DEE | 3 | Sandra who was the first to play "Gidget" |
| 37% | JACKIESTILES | 12 | 2016 Women's Basketball Hall of Fame inductee who was the first Division I player to score over 1,000 points in a season: 2 wds. |
| 37% | GUARINI | 7 | Justin, who was the first American Idol runner-up |
| 37% | NIMOY | 5 | Actor Leonard who was the first to play Spock |
| 37% | DEE | 3 | Actress Sandra who was the first to play Gidget |
| 37% | DEE | 3 | Actress Sandra who was the first to play "Gidget" |
| 37% | ALYN | 4 | Kirk ___, actor who was the first to play Superman |
| 37% | BIGMAMATHORNTON | 15 | Singer who was the first to record “Hound Dog” |
| 37% | ALEC | 4 | Baldwin who was the first to play Jack Ryan |
| 37% | AROD | 4 | Nickname of the ex-Yankee who was the youngest player to hit 600 home runs (Hyph.) |
| 37% | MARGARETCOURT | 13 | Australian tennis player who was the first woman to win the Grand Slam in the Open Era: 2 wds. |