| 100% | GEORGELOPEZ | 11 | Mexican-American comedian who starred on a self-titled sitcom: 2 wds. | 
| 72% | ELLENDEGENERES | 14 | Comedian who starred in a self-titled sitcom from 1994 to 1998: 2 wds. | 
| 72% | STEVEHARVEY | 11 | Comedian who starred in a self-titled sitcom from 1996 to 2002: 2 wds. | 
| 70% | GEORGELOPEZ | 11 | Comedian who starred in a self-titled sitcom from 2002 to 2007, and another that started in 2016: 2 wds. | 
| 67% | ANDYSAMBERG | 11 | Former "SNL" comedian who stars on a sitcom set in an NYPD precinct: 2 wds. | 
| 54% | JOHNAMOS | 8 | Actor who starred on "Good Times," a Norman Lear sitcom: 2 wds. | 
| 54% | SHERMANHEMSLEY | 14 | Actor who starred on "The Jeffersons," a Norman Lear sitcom: 2 wds. | 
| 53% | REDDFOXX | 8 | Actor who starred on "Sanford and Son," a sitcom developed by Norman Lear (who turns 100 today): 2 wds. | 
| 51% | CARROLLOCONNOR | 14 | Actor who starred on "All in the Family," a Norman Lear sitcom: 2 wds. | 
| 50% | JERRYSEINFELD | 13 | Comedian who played a fictional version of himself on a sitcom about "nothing" (2 wds.) | 
| 50% | ROSEANNEBARR | 12 | Title star of a 1990s sitcom who was the honoree of a 2012 Comedy Central  roast: 2 wds. | 
| 49% | MRT | 3 | Tough actor who starred on "The A-Team": 2 wds. | 
| 48% | MARTINLAWRENCE | 14 | Stand-up comedian and star of a 1990s Fox sitcom, whose title was his first name: 2 wds. | 
| 48% | JOHNMULANEY | 11 | Stand-up comedian who guest-stars as Stevie on a 2023 flashback episode of "The Bear": 2 wds. | 
| 47% | DELTABURKE | 10 | Actress (married to 33-Across) who starred on a 1982 soap opera parody also called 18-Across: 2 wds. | 
| 46% | LILYTOMLIN | 10 | Actress/comedian who stars on Netflix's "Grace and Frankie": 2 wds. | 
| 46% | MINHAJ | 6 | American comedian and writer Hasan ___ who has a comedy special on Netflix titled "Homecoming King" | 
| 46% | MARGARETCHO | 11 | Korean-American comedian who starred in "Drop Dead Diva": 2 wds. | 
| 45% | AARONSANCHEZ | 12 | Mexican-American celebrity chef who's a judge on "MasterChef": 2 wds. | 
| 44% | SHARONGLESS | 11 | Actress who starred as a cop on the 1982-1988 series "Cagney & Lacey": 2 wds. | 
| 44% | ANGIEDICKINSON | 14 | Actress who starred as a cop on the 1974-1978 series "Police Woman": 2 wds. | 
| 44% | CAROLBURNETT | 12 | Emmy-winning comedian who played a clumsy woman with a guardian angel on "The Twilight Zone": 2 wds. | 
| 44% | PEGGYLIPTON | 11 | Actress who starred as a cop on the 1968-1973 series "The Mod Squad": 2 wds. | 
| 43% | DANECOOK | 8 | Comedian who starred in "Good Luck Chuck": 2 wds. | 
| 43% | ROBINWILLIAMS | 13 | Comedian who stars in "The Crazy Ones": 2 wds. | 
| 42% | LINDSAYLOHAN | 12 | Actress who starred as both the twins in 29a, a 1998 hit based on the novel "Lottie and Lisa": 2 wds. | 
| 42% | MARCIABRADY | 11 | Maureen McCormick's character on a 1969-1974 family sitcom, who shares a last name with Patriots quarterback Tom: 2 wds. | 
| 41% | GINATORRES | 10 | "Firefly" actress who stars on "9-1-1: Lone Star": 2 wds. | 
| 41% | ROSIEODONNELL | 13 | Host of a self-titled talk show who hosted the 1999 and 2000 Grammy ceremonies: 2 wds. | 
| 41% | LARRYDAVID | 10 | Actor and comedian who created HBO's comedy series "Curb Your Enthusiasm" and stars in it as a fictionalized version of himself: 2 wds. |