| 100% | FOE | 3 | Moriarty, to Holmes |
| 100% | ADVERSARY | 9 | Moriarty, to Holmes |
| 100% | NEMESIS | 7 | Moriarty, to Holmes |
| 98% | NEMESES | 7 | Moriarty to Holmes and The Joker to Batman |
| 67% | AFOOT | 5 | Underway, to Holmes |
| 67% | AFOOT | 5 | Happening, to Holmes |
| 67% | AFOOT | 5 | Looming, to Holmes |
| 63% | AFOOT | 5 | In progress, to Holmes |
| 61% | GEM | 3 | The Blue Carbuncle, to Holmes |
| 61% | THEGAME | 7 | What's "afoot," to Holmes |
| 58% | ARCHFOES | 8 | Holmes and Moriarty, e.g. |
| 58% | ELEMENTARY | 10 | Holmes says this to watson |
| 56% | ALTEREGO | 8 | Holmes to Conan Doyle, e.g. |
| 55% | ALPS | 4 | Where Holmes grapples with Moriarty |
| 55% | KAREN | 5 | ___ Holmes, "From Here to Eternity" wife |
| 54% | IRENE | 5 | "The woman," to Sherlock Holmes |
| 54% | LANDLADY | 8 | Mrs. Hudson, to Sherlock Holmes |
| 54% | AFOOT | 5 | Under way, to Sherlock Holmes |
| 53% | PROFESSOR | 9 | __ James Moriarty, Sherlock Holmes' nemesis |
| 52% | NEMESIS | 7 | Archenemy, like Professor Moriarty for Sherlock Holmes |
| 51% | DANA | 4 | Capt. Holmes of "From Here to Eternity" |
| 51% | WATSON | 6 | Companion to the famous detective Sherlock Holmes |
| 51% | MYDEAR | 6 | Part of a Holmes comment to Watson |
| 51% | MYSTERY | 7 | Something for Sherlock Holmes to figure out |
| 51% | SUSSEX | 6 | English county where Sherlock Holmes retires to |
| 50% | ELEANOR | 7 | Longtime D.C. delegate to Congress ___ Holmes Norton |
| 50% | THEWOMAN | 8 | Sherlock Holmes referred to Irene Adler as this |
| 48% | TOM | 3 | Actor Cruise who was once married to Katie Holmes |
| 47% | ADLER | 5 | Irene who was the only woman to outwit Sherlock Holmes |
| 44% | DOYLE | 5 | Writer pressured by fans to bring Sherlock Holmes back from the dead |