| 100% | SMITH | 5 | Most common surname in the U.S. (ahead of Johnson and Williams) |
| 61% | SMITH | 5 | Most common surname in the U.S. |
| 44% | SMITH | 5 | Most common surname in the United States, according to the 2010 census |
| 43% | UNITED | 6 | What the U.S. and U.K. have in common? |
| 43% | TEAMMASCOT | 10 | An eagle is the most common one in the U.S. |
| 42% | STREETNAME | 10 | The most common one in the US is "2nd", oddly |
| 42% | ACNE | 4 | Most common skin condition in the U.S. |
| 42% | OPOSITIVE | 9 | Most common blood type in the U.S. |
| 42% | MAIN | 4 | Most common street name in the U.S. |
| 42% | FAULKNER | 8 | William __, U.S. author of The Sound and the Fury |
| 41% | JONES | 5 | Fifth-most-common U.S. surname, after Smith, Johnson, Williams and Brown |
| 41% | SMITH | 5 | The most common last name in the U.S. |
| 41% | CHICAGO | 7 | Most populated city in the US state of Illinois |
| 40% | BOARDWALK | 9 | Most expensive property in the US edition of 15-Across |
| 40% | RODRIGUEZ | 9 | Surname of the American League's Most Valuable Player in 1999, 2003, 2005 and 2007 |
| 40% | XXXXXXXXXXXX | 12 | Moves in the shape of A's, O's and U's at a disco? |
| 39% | YALE | 4 | Third-oldest college/university in the US (after Harvard and William & Mary) |
| 39% | LIAM | 4 | Most popular name for boys in the U.S. in 2017 and 2018 |
| 39% | BAGGINS | 7 | Frodo and Bilbo's surname in the Lord of the Rings |
| 39% | LABS | 4 | Most popular dogs in the U.S. |
| 39% | ETAL | 4 | And more of the same, in brief |
| 39% | LOS | 3 | First word in the name of the U.S.'s most populous county |
| 39% | UCLA | 4 | Most applied-to U.S. sch. in the fall of 2021 |
| 38% | NYC | 3 | Most populous city in the U.S.: Abbr. |
| 38% | ADAMS | 5 | Surname of the second and sixth US presidents |
| 38% | MBA | 3 | Degree that started materialising in the early 20's, and is one of the most sought after courses nowadays : Abbr. |
| 38% | DICAPRIO | 8 | Surname of an actor in Titanic and The Revenant |
| 38% | LOCO | 4 | El Pollo __: chain in the U.S. and Mexico |
| 38% | SDAK | 4 | Only U.S. state in which the name of the state and its capital share no letters: Abbr. |
| 38% | SMITH | 5 | Most common U.S. surname |