| 100% | OCTOBERSKY | 10 | Movie based on the memoir "Rocket Boys" (and an anagram of "Rocket Boys") |
| 56% | PRISCILLA | 9 | 2023 movie based on the memoir Elvis and Me |
| 55% | OLLIE | 5 | "Stan & ___," 2018 comedy movie based on the lives of Laurel and Hardy |
| 54% | BEOWULF | 7 | 2007 movie starring Anthony Hopkins and Ray Winstone, based on an Old English epic poem of the same name |
| 49% | TEMPLEGRANDIN | 13 | 2010 biographical drama film based on the life of an American scientist and autism advocate: 2 wds. |
| 48% | THIS | 4 | The thing right here, and an anagram of 38-Down |
| 46% | BLADERUNNER | 11 | Movie based on the book "Do Androids Dream of Electric Sheep?" |
| 46% | TAICHI | 6 | Discipline based on the principles of yin and yang |
| 46% | BROKEN | 6 | With 49-Across, it keeps repeating itself ... and, based on the first and last letters, an apt description of each answer to a starred clue |
| 46% | LESSOR | 6 | Landlord, and an anagram of the plural of 16 Down |
| 46% | HADESTOWN | 9 | Broadway musical based on the myth of Orpheus and Eurydice |
| 45% | ARGO | 4 | Best Picture winner based on the memoir "The Master of Disguise" |
| 45% | AMADEUS | 7 | Peter Shaffer play based on the lives of Mozart and Salieri |
| 45% | CLUE | 4 | 1985 movie based on a murder mystery board game of the same name where players identify the killer, their weapon, and the scene of crime |
| 45% | PAINTEDHOUSE | 12 | "A ___," a 2003 movie based on a John Grisham novel of the same name about a 7 year old boy named Luke Chandler: 2 wds. |
| 45% | ARGO | 4 | 2012 movie based on the Tony Mendez book "The Master of Disguise" |
| 45% | SULLY | 5 | 2016 Tom Hanks movie based on the true story of a pilot |
| 45% | ROALDDAHL | 9 | Writer of the children's books that the movies directed by 14-, 20-, and 36-Across were based on: 2 wds. |
| 44% | JOSIE | 5 | "___ and the Pussycats" (2001 movie based on a cartoon) |
| 44% | BADNEWSBEARS | 12 | Sports comedy, directed by Richard Linklater, based on an alcoholic baseball player and is also a reboot of 1976 film of the same name: 3 wds. |
| 44% | INVENTINGANNA | 13 | Shonda Rhimes miniseries starring 18-Across and 42-Across based on the true story of a con artist who pretended to be an heiress (2 wds.) |
| 44% | LAST | 4 | "Valentino: The ___ Emperor," movie based on the life of the eponymous designer from Italy |
| 43% | EPIC | 4 | 2013 animated movie based on the book "The Leaf Men and the Brave Good Bugs" |
| 43% | RICH | 4 | "Richie ___," 1994 Macaulay Culkin movie based on the Harvey Comics character of the same name |
| 43% | SPAN | 4 | Unit of length based on the width of an expanded hand |
| 43% | DUCK | 4 | "Howard the ___," 1986 Lea Thompson movie based on the Marvel Comics character of the same name |
| 43% | OCTOBERSKY | 10 | 1999 movie that is an adaptation, and an anagram, of 20-Across: 2 wds. |
| 42% | RED | 3 | "The Thin ___ Line," 1998 movie based on James Jones' novel about the WWII battle of Guadalcanal |
| 42% | GIA | 3 | Angelina Jolie starrer biographical film based on the life of an American supermodel |
| 42% | ANNE | 4 | "___ Boleyn," 2021 period drama series based on the life of an English Queen |