| 100% | SNL | 3 | NBC show hosted by Eddie Murphy in 2019 |
| 52% | CMAS | 4 | Awards show hosted by Underwood, McEntire and Parton in 2019 |
| 50% | TONYS | 5 | Awards show hosted in 2019 by James Corden |
| 44% | AXELFOLEY | 9 | He was played by Eddie Murphy in Beverly Hills Cop |
| 42% | NICKNEWS | 8 | Show hosted by Linda Ellerbee that began airing in the early nineties |
| 41% | SNL | 3 | NBC show that gave Eddie Murphy and Tina Fey their start: Abbr. |
| 40% | DOLITTLE | 8 | John ___, fictional doctor played by Eddie Murphy in the 1998 film based on Hugh Lofting's stories |
| 40% | EMMYS | 5 | Awards show hosted in 2014 by Seth Meyers |
| 40% | ESPY | 4 | Award show hosted by Lance Armstrong in 2006 |
| 40% | ESPY | 4 | Award show hosted by LeBron James in 2007 |
| 40% | ESPYS | 5 | Awards show hosted by Steph Curry in 2022 |
| 40% | SURVIVOR | 8 | CBS reality show hosted by Jeff Probst whose first version aired in Sweden |
| 40% | SNL | 3 | NBC show whose first episode was hosted by George Carlin, for short |
| 40% | SNL | 3 | NBC show that 33-Across hosted in 2010 at age 88: Abbr. |
| 39% | SNL | 3 | Show for which Eddie Murphy won an Emmy, in brief |
| 39% | AMAS | 4 | Awards show hosted by Cardi B in 2021, for short |
| 39% | BATTLESTARS | 11 | American game show hosted by Alex Trebek during the 1980's that aired on NBC |
| 39% | SURVIVOR | 8 | American reality show hosted by Jeff Probst, where contestants are marooned in an isolated location |
| 39% | SNL | 3 | NBC comedy show hosted by Melissa McCarthy five times, for short |
| 39% | SNL | 3 | NBC comedy show hosted by Tom Hanks 10 times, for short |
| 39% | SURVIVOR | 8 | TV show hosted in US by Jeff Probst for 40 seasons |
| 39% | ESPYS | 5 | Sports awards show hosted by Peyton Manning in 2017 |
| 39% | BIGBROTHER | 10 | CBS reality show hosted by Julie Chen whose first version aired in the Netherlands: 2 wds. |
| 37% | TONYS | 5 | Theater awards ceremony hosted by James Corden in 2019 |
| 37% | THEVOICE | 8 | American reality show hosted by Carson Daly, which works in a format similar to 21-Across: 2 wds. |
| 37% | SNL | 3 | NBC sketch comedy show hosted by Alec Baldwin a record 17 times (Abbr.) |
| 36% | TODAY | 5 | Show hosted by Katie Couric |
| 36% | JEOPARDY | 8 | Show hosted by Alex Trebek |
| 36% | LOVEISBLIND | 11 | Netflix reality dating show hosted by Nick and Vanessa Lachey featuring couples who get engaged before meeting in person (3 wds.) |
| 35% | FATHERKNOWSBETS | 15 | Show hosted by a Vegas priest? |