| 100% | BENBRADLEE | 10 | Newspaper editor played by Tom Hanks in "The Post" (2 wds.) |
| 99% | BENBRADLEE | 10 | Real-life newspaper editor played by Tom Hanks in "The Post": 2 wds. |
| 66% | MISTERROGERS | 12 | TV host played by Tom Hanks in "A Beautiful Day in the Neighborhood" (2 wds.) |
| 63% | CHARLIEWILSON | 13 | Title role played by Tom Hanks in a 2007 comedy-drama: 2 wds. |
| 63% | LARRYCROWNE | 11 | Title role played by Tom Hanks in a 2011 romantic comedy: 2 wds. |
| 63% | CHARLIEWILSON | 13 | Real-life congressman played by Tom Hanks in a 2007 movie: 2 wds. |
| 63% | FORRESTGUMP | 11 | Title role played by Tom Hanks in a 1994 Oscar-winning movie: 2 wds. |
| 63% | TOMPARKER | 9 | Real-life talent manager and "Colonel" played by Tom Hanks in "Elvis": 2 wds. |
| 62% | JIMLOVELL | 9 | Real-life astronaut played by Tom Hanks in "Apollo 13": 2 wds. |
| 62% | WALTDISNEY | 10 | Real-life Oscar-winning animator played by Tom Hanks in a 2013 movie: 2 wds. |
| 62% | FREDROGERS | 10 | Real-life children's entertainer played by Tom Hanks in a 2019 movie: 2 wds. |
| 62% | WALTDISNEY | 10 | Real-life animator and film producer played by Tom Hanks in "Saving Mr. Banks": 2 wds. |
| 59% | WALTDISNEY | 10 | Animation pioneer played by Tom Hanks in "Saving Mr. Banks" (2 wds.) |
| 58% | BRADLEE | 7 | Editor played by Hanks in "The Post" |
| 53% | FORRESTGUMP | 11 | Tom Hanks' 1994 drama film based on a Winston Groom novel of the same name in which 20a plays his love interest: 2 wds. |
| 51% | GREGSHORT | 9 | Character played by Colin Hanks in "Life in Pieces": 2 wds. |
| 48% | ETHANHUNT | 9 | Fictional spy played by Tom Cruise in "Mission: Impossible" film series: 2 wds. |
| 48% | MEHRANKARIMI | 12 | Actor Tom Hanks's character in 2004 comedy-drama "The Terminal" which was inspired by a real-life person named ___ Nasseri: 2 wds. |
| 48% | JACKSPARROW | 11 | Pirate played by Johnny Depp in the "Pirates of the Caribbean" movies: 2 wds. |
| 48% | ITSOK | 5 | "___", song by Tom Rosenthal, featured in the trailers of "Comet" and "Anesthesia" : 2 wds. |
| 48% | STARRCARTER | 11 | Character played by Amandla Stenberg in the movie adaptation of 30-Across: 2 wds. |
| 48% | HEATHERLEE | 10 | Character played by Alicia Vikander in the action spy movie "Jason Bourne": 2 wds. |
| 48% | CLOUDATLAS | 10 | 2012 Tom Hanks fantasy film directed by the Wachowski sisters (with Tom Tykwer): 2 wds. |
| 48% | CLARKKENT | 9 | The lead character in "Smallville" who eventually becomes Superman, played by Tom Welling: 2 wds. |
| 47% | JACKIEROBINSON | 14 | Baseball superstar played by Chadwick Boseman in the 2013 biopic "42": 2 wds. |
| 47% | JIM | 3 | Astronaut Lovell who was played by Tom Hanks in "Apollo 13" |
| 47% | VITOCORLEONE | 12 | Mafia don played by both 14-Across and 28-Across in the "Godfather" franchise: 2 wds. |
| 47% | SWEENEYTODD | 11 | Barber played by Johnny Depp in the movie subtitled "The Demon Barber of Fleet Street": 2 wds. |
| 46% | LORETTALYNN | 11 | Country singer played by 44-Across in the 1980 biopic "Coal Miner's Daughter": 2 wds. |
| 46% | EDITHBUNKER | 11 | Housewife played by 29-Across in "All in the Family": 2 wds. |