| 100% | WIIU | 4 | Nintendo console that was replaced by the Switch: 2 wds. |
| 52% | SOLARCAR | 8 | Vehicle that is powered by the sun: 2 wds. |
| 47% | LIRA | 4 | Currency from 45-Down that was replaced by the euro |
| 47% | WIIU | 4 | Console succeeded by Nintendo Switch: 2 wds. |
| 46% | LTD | 3 | Ford model that was replaced by the Crown Victoria and the Taurus |
| 46% | WII | 3 | Nintendo console that preceded the Switch |
| 46% | STAYINALIVE | 11 | Disco hit by the Bee Gees that was a part of the "Saturday Night Fever" soundtrack: 2 wds. |
| 45% | HEYMAMA | 7 | 2004 song by the Black Eyed Peas that was nominated for a Grammy for Best Rap Song: 2 wds. |
| 45% | COTTONEYEDJOE | 13 | Traditional American folk song that was the inspiration for a 1994 hit by Swedish band Rednex: 2 wds., hyph. |
| 45% | CADILLACRANCH | 13 | 1980 Bruce Springsteen song that was covered by the Nitty Gritty Dirt Band: 2 wds. |
| 45% | BARBARAANN | 10 | 1965 Beach Boys hit that was first recorded by the Regents: 2 wds. |
| 44% | MISTYMOUNTAIN | 13 | "___ Hop" 1971 song by the rock band Led Zeppelin that which was a part of their untitled fourth album: 2 wds. |
| 43% | GAMEBOYS | 8 | Nintendo consoles introduced in the US in 1989: 2 wds. |
| 43% | WIIU | 4 | Game console that preceded the Nintendo Switch |
| 42% | WIIU | 4 | Nintendo console succeeded by the Switch |
| 42% | EWINGOIL | 8 | Company that was the focus of "Dallas": 2 wds. |
| 41% | PETERGABRIEL | 12 | Lead singer of Genesis who was replaced by Phil Collins in 1975: 2 wds. |
| 41% | ITSSOSAD | 8 | Phrase that might be replaced by the Crying Face emoji |
| 41% | EMBRACEABLEYOU | 14 | Song by 16-Across that was introduced by Ginger Rogers in the musical "Girl Crazy": 2 wds. |
| 41% | IFSO | 4 | "Should that be the case ...": 2 wds. |
| 41% | LADYMARMALADE | 13 | A popular song that was covered by Christina Aguilera, Lil' Kim, Mya and Pink for the soundtrack of "Moulin Rouge!": 2 wds. |
| 41% | ELMTREE | 7 | A tree that is the state symbol for Massachusetts: 2 wds. |
| 40% | OZZYOSBOURNE | 12 | Lead singer of Black Sabbath who was replaced by Ronnie James Dio in 1979: 2 wds. |
| 40% | HAPPYTOGETHER | 13 | 1967 song by 15-Across that was the group's biggest hit: 2 wds. |
| 40% | MOTIONPICTURE | 13 | Entertainment medium that was largely developed by 20-/37-Across: 2 wds. |
| 40% | NORWEGIANWOOD | 13 | 1965 "country" song by the Beatles that features a sitar: 2 wds. |
| 40% | SANFRANCISCO | 12 | West Coast city that will host the 2025 Laver Cup: 2 wds. |
| 40% | REDSEA | 6 | Body of water that was parted by Moses : 2 wds. |
| 40% | LABOHEME | 8 | Opera by Puccini that is the basis for the film "Rent" (2 wds) |
| 40% | AFTERHOURS | 10 | 2020 #1 album by The Weeknd whose lead single is "Heartless": 2 wds. |