| 100% | RAPACE | 6 | Noomi —, actress who played Madam Simza Heron in 2011 adventure film Sherlock Holmes: A Game of Shadows |
| 97% | RAPACE | 6 | Noomi —, Swedish actress who played Madam Simza Heron in 2011 adventure film Sherlock Holmes: A Game of Shadows |
| 38% | ZUCCO | 5 | George —, Manchester-born actor who played Professor Moriarty in 1939 film drama The Adventures of Sherlock Holmes |
| 37% | SHADOWS | 7 | A Game of __, title of a 2011 Sherlock Holmes film |
| 35% | DOOLEY | 6 | Taylor ___, actress who plays Lavagirl in the film "The Adventures of Sharkboy and Lavagirl" |
| 35% | SEAGROVE | 8 | Jenny —, actress who played Fay Hubbard in 1989 comedy-drama film A Chorus of Disapproval |
| 35% | MIAWASIKOWSKA | 13 | Australian actress who plays Jane Eyre in a 2011 Cary Joji Fukunaga film (2 wds.) |
| 35% | ZOESALDANA | 10 | "Avatar" actress who played a pirate in the first "Pirates of the Caribbean" film: 2 wds. |
| 35% | NIGEL | 5 | Actor Bruce who played Watson in "The New Adventures of Sherlock Holmes" |
| 35% | DIANELANE | 9 | "Unfaithful" actress who plays Penny Chenery, the owner of 33-Across, in a 2010 film (2 wds.) |
| 34% | SUMAC | 5 | Yma —, Peru-born singer and actress who played Kori-Tica in 1954 adventure film Secret of the Incas |
| 34% | COOK | 4 | Peter ___, actor who played Sherlock Holmes in the 1978 British film "The Hound of the Baskervilles" |
| 33% | NANCYTRAVIS | 11 | "The Kominsky Method" actress who plays the grandmother of a critically ill girl in the 2024 film "Ordinary Angels" (2 wds.) |
| 33% | OLGA | 4 | Actress Kurylenko who played a Bond girl in the 2008 film "Quantum of Solace" |
| 32% | RACHELMCADAMS | 13 | "True Detective" actress who played 32-Across in the Guy Ritchie film "Sherlock Holmes" (2 wds.) |
| 32% | WHOOPIGOLDBERG | 14 | "Sister Act" actress who played God in the films "A Little Bit of Heaven" and "It's a Very Merry Muppet Christmas Movie" (2 wds.) |
| 32% | STEPHENS | 8 | Robert —, actor who played the title role in 1970 comedy-adventure film The Private Life of Sherlock Holmes |
| 32% | STELLA | 6 | Actress who played Linda Rogo in 1972 action film The Poseidon Adventure |
| 32% | KATYA | 5 | Actress who played Countess Mircalla in 1971 horror film Twins of Evil |
| 32% | IRENE | 5 | Rachel McAdams's role in "Sherlock Holmes: A Game of Shadows" |
| 32% | DIANEKEATON | 11 | Actress who plays a mother in "Father of the Bride" (2 wds.) |
| 32% | RUSSO | 5 | Rene —, actress who played Frigga in 2011 action film Thor |
| 32% | RENE | 4 | & 23A Actress who played Frigga in 2011 action film Thor |
| 31% | PEET | 4 | Amanda —, actress who played Kate Curtis in 2009 adventure film 2012 |
| 31% | PEET | 4 | Amanda -, actress who played Kate Curtis in 2009 adventure film 2012 |
| 31% | STONE | 5 | Emma —, actress who played Skeeter Phelan in 2011 film The Help |