| 100% | MOBYDICK | 8 | Novel that opens with the line "Call me Ishmael" |
| 68% | MOBYDICK | 8 | Melville novel with the line "Call me Ishmael" |
| 54% | RIGHTEOUS | 9 | 2020 Juice WRLD song that opens with the line "All-white Gucci suit" |
| 51% | JANEEYRE | 8 | Novel with the line "Reader, I married him" |
| 49% | MOBY | 4 | With 5-Down, novel that begins "Call me Ishmael" |
| 47% | HELLO | 5 | 48-Down song with the line "But when I call, you never seem to be home" |
| 47% | TNT | 3 | AC/DC song that ends with the line “Watch me explode” |
| 47% | IWONTBACKDOWN | 13 | Tom Petty song with the line "In a world that keeps on pushin' me around" (4 wds.) |
| 45% | LEAR | 4 | King with the immortal line "Who is it that can tell me who I am?" |
| 44% | CASABLANCA | 10 | 1942 film that ends with the line “Louis, I think this is the beginning of a beautiful friendship” |
| 43% | IROBOT | 6 | Classic 1950 book with the line "It's your fiction that interests me. Your studies of the interplay of human motives and emotion" |
| 43% | DRNO | 4 | Movie with the opening line "I admire your courage, Miss …?" |
| 42% | LORRE | 5 | Actor with the line "Rick! Rick, help me!" |
| 42% | BELOVED | 7 | 1987 novel with the opening lines “124 was spiteful. Full of a baby’s venom” |
| 42% | RENT | 4 | 1996 Broadway musical that opens with the words "We begin on Christmas Eve ..." |
| 41% | SOS | 3 | Rihanna song with the line "Please someone help me" |
| 41% | KARMAPOLICE | 11 | 1997 Radiohead hit that ends with the repeated line "For a minute there / I lost myself" |
| 41% | TAXIDRIVER | 10 | De Niro movie with the line "You talkin' to me?" |
| 41% | SOS | 3 | 2006 Rihanna song with the line "Please someone help me" |
| 41% | THECHOSEN | 9 | Chaim Potok novel that opens with a baseball game between modern Orthodox and Hasidic Jews |
| 40% | HANSOLO | 7 | Sci-fi hero with the line "Never tell me the odds" |
| 40% | HEYMRDJ | 7 | 1990s hit with the line "keep playing that song, all night" |
| 40% | MEXICANGOTHIC | 13 | Silvia Moreno-Garcia novel with the lines “The walls speak to me. They tell me secrets” |
| 40% | TWINPEAKS | 9 | TV show that concluded with the line “I’ll see you again in twenty-five years” |
| 40% | SHREK | 5 | Animated movie with the line "That'll do, Donkey, that'll do" |
| 40% | THESANDLOT | 10 | Sports movie with the line "You're killing me, Smalls!" (2 wds.) |
| 40% | GEMS | 4 | Uncut ___ (Adam Sandler movie with the line "This is how I win") |
| 39% | HANSOLO | 7 | Fictional pilot with the line "You like me because I'm a scoundrel" |
| 39% | ITOO | 4 | Hughes poem with the line "They send me to eat in the kitchen" |
| 39% | ODEONMELANCHOLY | 15 | Keats work with the line, "She dwells with Beauty--Beauty that must die" |