| 100% | IRIS | 4 | Novelist Murdoch who was played by Kate Winslet and Judi Dench in a 2001 biopic |
| 45% | IRIS | 4 | Author Murdoch played onscreen by Kate Winslet and Judi Dench |
| 44% | IRIS | 4 | 2001 film in which Kate Winslet and Judi Dench played the title role |
| 43% | IRIS | 4 | Murdoch who was played by Judi Dench |
| 43% | IRIS | 4 | 2001 biopic featuring both Judi Dench and Kate Winslet in the title role |
| 39% | IRISMURDOCH | 11 | Dench and Winslet, in a 2001 biopic |
| 37% | ALI | 3 | Boxer played by Will Smith in a 2001 biopic |
| 37% | ALI | 3 | Whom Will Smith played in a 2001 sports biopic |
| 36% | MUHAMMADALI | 11 | Boxer played by Will Smith in a 2001 biopic (2 wds.) |
| 36% | ALI | 3 | Boxer Muhammad played by Will Smith in a 2001 biopic |
| 35% | ETTA | 4 | Singer James who was played by Beyoncé in a movie |
| 35% | EVA | 3 | Perón who was played by Madonna in a movie musical |
| 35% | EVA | 3 | Perón who was played by Madonna in a 1996 movie |
| 35% | ETTA | 4 | James who was played by Beyoncé in the biopic "Cadillac Records" |
| 35% | EVA | 3 | Perón who was played by Madonna in a 1996 movie musical |
| 34% | ENOLA | 5 | Holmes who was played by Millie Bobby Brown in 2020 and 2022 |
| 34% | OPHELIA | 7 | Noblewoman played by Helena Bonham Carter, Kate Winslet, and Daisy Ridley in film versions of a Shakespeare play |
| 33% | EVA | 3 | Political leader Perón who was played in a movie by Madonna |
| 33% | JESSEPINKMAN | 12 | Character played by Aaron Paul in "Breaking Bad", who was a crystal meth dealer and worked with the character played by 30-Across: 2 wds. |
| 33% | TOMBRAIDER | 10 | Game whose heroine was played by Angelina Jolie in a 2001 film |
| 33% | IRIS | 4 | 2001 biopic about writer Murdoch, in which 15-Across played the title role (and received a Best Actress nomination) |
| 33% | EARP | 4 | Old West lawman Wyatt who was played in a movie by Kevin Costner |
| 31% | ALI | 3 | Boxer portrayed by Will Smith in a 2001 biopic |
| 31% | ALI | 3 | Boxer played in a biopic by Will Smith |
| 31% | COSMOKRAMER | 11 | Character played by Michael Richards in "Seinfeld", who is 32-Across's neighbor and is often called a "hipster doofus": 2 wds. |
| 31% | IRIS | 4 | Murdoch played by Kate Winslet |
| 30% | NITTI | 5 | Frank who was played by Stallone in "Capone" |
| 30% | ETTA | 4 | Singer ___ James who was played by Beyoncé in "Cadillac Records" |
| 30% | ORSON | 5 | Director Welles who was played by Tom Burke in "Mank" |
| 30% | HANNIBAL | 8 | Horror thriller TV series named after the protagonist who is a forensic psychiatrist and cannibal played by Mads Mikkelsen |