| 100% | RENAL | 5 | Of interest to a nephrologist, perhaps |
| 68% | GED | 3 | Tests you can take that may later be of interest to a high school dropout, perhaps (abbr.) |
| 65% | NICHE | 5 | Of interest to a few |
| 65% | RARE | 4 | Of interest to a collector, say |
| 63% | TOES | 4 | Digits of interest to a pedicurist |
| 63% | BANKLOAN | 8 | Something of interest to a business? |
| 63% | RDA | 3 | Fig. of interest to a dietitian |
| 63% | APE | 3 | Animal of interest to a primatologist |
| 63% | ERA | 3 | Period of interest to a historian |
| 62% | GENE | 4 | Subject of interest to a 23andMe user |
| 62% | DIARY | 5 | Book of interest to a nosy sibling |
| 62% | STAT | 4 | Tidbit of interest to a FIFA gamer |
| 62% | EDITION | 7 | Detail of interest to a book collector |
| 62% | HOUSELOAN | 9 | Something of interest to a home buyer? |
| 61% | TIME | 4 | Stat of interest to a competitive crossword solver |
| 61% | MINDMELD | 8 | Link of interest to a “Star Trek” fan |
| 56% | RARE | 4 | Of particular interest to a completist |
| 55% | RAREST | 6 | Of greatest interest to a bibliophile, maybe |
| 55% | IDO | 3 | Statement to a justice of the peace, perhaps |
| 54% | GARNISH | 7 | Piece of interest added to a plate of food |
| 54% | ONHOLD | 6 | Listening to a looped clip of classical music, perhaps |
| 53% | SUGARPILL | 9 | “Medication” given to a member of the control group, perhaps |
| 51% | TENAM | 5 | When to grab a second cup of coffee, perhaps |
| 50% | SWIPELEFT | 9 | Express lack of interest on Tinder ... or a hint to the answers to starred clues |
| 49% | AVIAN | 5 | Of interest to Audubon |
| 49% | ANCIENT | 7 | Of interest to archaeologists |
| 49% | AVIAN | 5 | Of interest to ornithologists |
| 49% | NOSY | 4 | Interested to a fault |
| 49% | ECHO | 4 | Effect of a Twitch guest forgetting to mute their stream, perhaps |
| 49% | AVIAN | 5 | Of interest to bird-watchers |