| 100% | VITAL | 5 | Of utmost importance, as some signs |
| 78% | VITAL | 5 | Of utmost importance, like some signs or organs |
| 53% | OMEN | 4 | Sign of things to come, as an eclipse, to some |
| 52% | VITAL | 5 | Of utmost importance |
| 50% | VITAL | 5 | Crucial or of utter importance, such as ___ signs |
| 44% | NRA | 3 | Target of some student walkout signs |
| 44% | EDIT | 4 | Change, as some of these clues |
| 44% | EST | 3 | As of, on signs |
| 44% | MIST | 4 | Sign of some springs |
| 43% | ODOR | 4 | Sign of some gas leaks |
| 43% | ARROW | 5 | Shape of some one-way signs |
| 43% | VITAL | 5 | Of the utmost importance |
| 43% | CLEF | 4 | Sign in front of some bars |
| 42% | ENDORSES | 8 | Signs, as the back of a check |
| 42% | CLEF | 4 | Sign seen in front of some bars |
| 42% | CLEF | 4 | Sign at the front of some bars |
| 42% | ENDORSE | 7 | Sign, as the back of a check |
| 42% | NEONRED | 7 | Color of some exit signs |
| 41% | REUP | 4 | Sign on, as for another tour of duty |
| 41% | ENDORSE | 7 | Sign, as the reverse side of a check |
| 41% | RANK | 4 | Classify, as in order of importance |
| 41% | NODS | 4 | Head gestures as signs of approval |
| 41% | FORESTFIRES | 11 | Subjects of some park sign warnings |
| 41% | UNIBROW | 7 | Sign of lycanthropy, to some |
| 40% | ENDORSED | 8 | Signed for deposit, as the back of a check |
| 40% | YESON | 5 | First words of some political yard signs |
| 40% | USES | 4 | Applications or purposes, as of some equipment |
| 40% | CROPCIRCLE | 10 | Sign of alien life, some say |
| 40% | BEARD | 5 | Sign of religious devotion, for some |
| 39% | ALIENVISITS | 11 | What some think 43-Across are signs of |