| 100% | MOIRA | 5 | Offred's best friend from "The Handmaid's Tale" |
| 60% | MARTHAS | 7 | Green-outfitted servants from The Handmaid's Tale |
| 51% | ARE | 3 | "___ there any questions?" closing line from "The Handmaid's Tale" |
| 48% | ATWOOD | 6 | The Handmaid's Tale author Margaret |
| 48% | DOG | 3 | Jake the ___, Finn's best friend from the animated series "Adventure Time," who is associated with the color at 42a |
| 47% | ATWOOD | 6 | Margaret __, wrote The Handmaid's Tale |
| 47% | ATWOOD | 6 | Author of The Handmaid's Tale |
| 47% | ELISABETHMOSS | 13 | "Mad Men" actress who plays Offred in "The Handmaid's Tale": 2 wds. |
| 46% | OTTAWAN | 7 | The Handmaid's Tale's Margaret Atwood, for one |
| 46% | OFFRED | 6 | Main character in The Handmaid's Tale |
| 46% | MILHOUSE | 8 | Bart's best friend in The Simpsons |
| 45% | OFFRED | 6 | Chief character who narrates The Handmaid's Tale |
| 45% | PAULIE | 6 | Rocky's best friend in the "Rocky" films |
| 45% | MORDECAI | 8 | Rigby's best friend on the Regular Show |
| 45% | SERENAJOY | 9 | The Commander's wife in The Handmaid's Tale |
| 45% | DYSTOPIAN | 9 | Genre that The Handmaid's Tale is written as |
| 45% | FLOUNDER | 8 | Fish, Ariel's best friend in The Little Mermaid |
| 44% | BARNEY | 6 | Fred's best friend in the animated sitcom "The Flintstones" |
| 44% | NED | 3 | Peter Parker's best friend in the "Spider-Man" franchise |
| 44% | ARF | 3 | Call from one's best friend? |
| 43% | NED | 3 | Leeds who is Spider-Man's best friend in the MCU movies |
| 42% | DAFFYDUCK | 9 | Best friend and occasional rival of 15-Across, the iconic black duck from "Looney Tunes": 2 wds. |
| 42% | MIDGE | 5 | Barbie the doll's best friend |
| 42% | GILEAD | 6 | Where the majority of the "The Handmaid's Tale" takes place |
| 42% | DEMURE | 6 | Like a lot of the attire in "The Handmaid's Tale" |
| 42% | SAMWISE | 7 | Frodo's best friend in Lord of the Rings |
| 42% | GRETEL | 6 | Hansel's sister from the fairy tale |
| 42% | TAXREFUND | 9 | Good news from the IRS |
| 42% | CHANDLER | 8 | Joey's best friend in the sitcom "F.R.I.E.N.D.S" |
| 42% | SHIRLEY | 7 | Laverne's best friend in the 1970s sitcom starring Penny Marshall and Cindy Williams |