| 100% | REESE | 5 | One of Malcolm's older brothers on "Malcolm in the Middle" |
| 72% | REESE | 5 | Older brother of Malcolm on "Malcolm in the Middle" |
| 66% | REESE | 5 | One of the brothers on "Malcolm in the Middle" |
| 62% | REESE | 5 | Brother of Malcolm on "Malcolm in the Middle" |
| 62% | REESE | 5 | The second-oldest brother on "Malcolm in the Middle" |
| 53% | EARP | 4 | One of three brothers in the Old West |
| 52% | BOSS | 4 | "___ of Me" (They Might Be Giants song featured on "Malcolm in the Middle") |
| 51% | HAL | 3 | Malcolm's dad on "Malcolm in the Middle" |
| 51% | HAL | 3 | Malcolm's father on "Malcolm in the Middle" |
| 51% | LOIS | 4 | Malcolm's mother on "Malcolm in the Middle" |
| 51% | ZEPPO | 5 | One of the brothers in a garbage can on a ''Time'' cover (1932) |
| 51% | HARPO | 5 | One of the brothers in a garbage can on a ''Time'' cover (1932) |
| 50% | RON | 3 | One of Fred Weasley's brothers in the "Harry Potter" books |
| 49% | HAL | 3 | Lois's husband on "Malcolm in the Middle" |
| 49% | HAL | 3 | Lois's husband, on "Malcolm in the Middle" |
| 49% | HAL | 3 | Bryan Cranston's role on "Malcolm in the Middle" |
| 49% | HAL | 3 | Bryan Cranston's character, on "Malcolm in the Middle" |
| 49% | ELI | 3 | One of the brothers on the NFL's "Manningcast" |
| 48% | TWIXT | 5 | In the middle of, old-style |
| 48% | VEE | 3 | One in the middle of Knoxville? |
| 48% | TANIA | 5 | Actress Raymonde of Lost and Malcolm in the Middle |
| 47% | ESAU | 4 | Older brother of Jacob, in the Bible |
| 47% | CAIN | 4 | Elder brother of Seth, in the Bible |
| 47% | REF | 3 | One in the middle of a fight |
| 47% | SONIC | 5 | One of the S's in SST |
| 47% | ARGOS | 5 | Greek city that's one of the oldest in Europe |
| 47% | EDIE | 4 | One of Frankie's aunts, on "The Middle" |
| 47% | PUTDOWNTHEPHONE | 15 | Advice for someone who's in the middle of deeply embarrassing themselves on social media |
| 47% | FRANKIEMUNIZ | 12 | Actor who played child prodigy Malcolm on "Malcolm in the Middle": 2 wds. |
| 47% | FRANKIEMUNIZ | 12 | "Malcolm in the Middle" actor who was a finalist on season 25 of "Dancing with the Stars" (2 wds.) |