| 100% | APOSTLE | 7 | One of the first disciples |
| 75% | OLDS | 4 | One of the first automakers |
| 75% | CREE | 4 | One of the First Nations |
| 75% | ADAM | 4 | One of the first mates |
| 74% | INCA | 4 | One of the first potato farmers |
| 73% | CREE | 4 | One of the First Nations of Canada |
| 73% | JAMESMONROE | 11 | One of the first five 49-Acrosses |
| 73% | JOHNADAMS | 9 | One of the first five 49-Acrosses |
| 73% | THOMASJEFFERSON | 15 | One of the first five 49-Acrosses |
| 73% | AOL | 3 | One of the first Internet service providers |
| 72% | ANGELS | 6 | One of the first two MLB expansion teams |
| 72% | CHATROOM | 8 | One of the first ways to communicate online |
| 72% | COBB | 4 | One of the first five inductees at Cooperstown |
| 72% | SIT | 3 | One of the first commands a puppy learns |
| 72% | FIG | 3 | One of the first fruits cultivated by humans |
| 72% | PHONE | 5 | One of the first words E.T. learns |
| 72% | EMMELINE | 8 | __ Pankhurst, one of the first Suffragettes |
| 71% | ALDRIN | 6 | One of the first men on the moon, Buzz |
| 71% | YEA | 3 | One of the first to raise a hand, usually |
| 71% | JONASSALK | 9 | One of the first to develop a polio vaccination |
| 71% | ARP | 3 | One of the first artists to incorporate random chance |
| 71% | BAEZ | 4 | One of the first to record Dylan's songs |
| 71% | PHONE | 5 | One of the first words Gertie teaches E.T. |
| 71% | LOVELACE | 8 | Ada, one of the first computer programmers |
| 71% | TWENTIETHCENTURY | 16 | One of the first Buicks to roll off the line? |
| 70% | PETER | 5 | One of the disciples of Jesus |
| 70% | MICKEY | 6 | __ Mouse is one of the first Disney icons |
| 70% | BUFFALOBILL | 11 | One of the first two ''American superstars,'' per 34 Across' book |
| 70% | ANNIEOAKLEY | 11 | One of the first two ''American superstars,'' per 34 Across' book |
| 70% | APOSTLE | 7 | One of the twelve disciples of Jesus |