| 100% | WASHINGTON | 10 | One of the first two states to permit marijuana for recreational use |
| 100% | COLORADO | 8 | One of the first two states to permit marijuana for recreational use |
| 45% | OMAR | 4 | Ilhan ___, one of the first two Muslim women elected to Congress |
| 44% | OMAR | 4 | Minnesotan Ilhan who is one of the first two Muslim women elected to Congress |
| 43% | BABYLON | 7 | "___ 5," one of the first television series to use CGI as the primary method for its visual effects |
| 42% | THISISLANDEARTH | 15 | 1955 sci-fi film that was one of the first to use Technicolor |
| 42% | AOXOMOXOA | 9 | Palindromic 1969 rock album that was one of the first to use 16-track technology |
| 41% | INDIEGOGO | 9 | Online platform that was one of the first websites to offer crowdfunding for business and personal goals |
| 41% | TENZINGNORGAY | 13 | Sherpa who was one of the first two people to conquer Mount Everest: 2 wds. |
| 40% | ANGELS | 6 | One of the first two MLB expansion teams |
| 39% | BUFFALOBILL | 11 | One of the first two ''American superstars,'' per 34 Across' book |
| 39% | ANNIEOAKLEY | 11 | One of the first two ''American superstars,'' per 34 Across' book |
| 38% | CHATROOM | 8 | One of the first ways to communicate online |
| 38% | EDMUNDHILLARY | 13 | New Zealand mountaineer who was one of the first two people to conquer Mount Everest: 2 wds. |
| 38% | YEA | 3 | One of the first to raise a hand, usually |
| 38% | JONASSALK | 9 | One of the first to develop a polio vaccination |
| 38% | ARP | 3 | One of the first artists to incorporate random chance |
| 38% | BAEZ | 4 | One of the first to record Dylan's songs |
| 38% | TWENTIETHCENTURY | 16 | One of the first Buicks to roll off the line? |
| 37% | ELSA | 4 | One of two Disney characters singing "For the First Time in Forever" |
| 37% | ALA | 3 | One of the two states bordering Florida: Abbr. |
| 37% | INTESTINE | 9 | One of the organs used to process food |
| 37% | BYRONSCOTT | 10 | One of the greatest players of the LA Lakers who won three NBA Championships and went on to coach the team for two years: 2 wds. |
| 36% | RAMIMALEK | 9 | Actor who became the first one of Egyptian heritage to win an Oscar for Best Actor in 2019: 2 wds. |
| 36% | ICET | 4 | One of the first musicians to have an "explicit content" sticker on an album |
| 36% | URDU | 4 | One of the two official languages used in Quetta, Balochistan |
| 36% | JOHNMADDEN | 10 | Football player turned broadcaster who was the first one to have worked for all of the "Big Four" TV networks: 2 wds. |
| 36% | HAROLD | 6 | One of the two film stoners who "go to White Castle" |
| 35% | MALIK | 5 | Surname of the first member to leave One Direction |
| 35% | DENIER | 6 | Unit of weight used for measuring the fineness of silk equal to one gram per 9,000 metres |