| 100% | BIGBANG | 7 | One of the theories of how the universe began |
| 67% | BIGBANG | 7 | Theory on how the universe began |
| 66% | BANG | 4 | The Big ___, theory for how the Universe began |
| 60% | BIGBANG | 7 | Scientific theory of the universe's beginning |
| 52% | PRATT | 5 | One of the Chrises of the Marvel Cinematic Universe |
| 50% | MASTERS | 7 | He-Man is one of the __ of the Universe |
| 49% | BIGBANG | 7 | Beginning of the universe |
| 49% | RAJ | 3 | One of the geeks on "The Big Bang Theory" |
| 47% | DNATEST | 7 | Lizzo takes one in the beginning of "Truth Hurts" |
| 47% | TIEATIE | 7 | One of the top how-to searches is how to do this |
| 47% | ERROL | 5 | One of the Weasley family's owls, in the Harry Potter universe |
| 47% | TREKKIE | 7 | Any one of the male "Big Bang Theory" main characters |
| 47% | BIGBANG | 7 | Theory that explains the creation of our universe |
| 46% | DEIST | 5 | Adherent of the clockwork universe theory |
| 45% | VERBATIM | 8 | How one is supposed to repeat the Oath of Allegiance |
| 45% | DAYTODAY | 8 | How one lives in the face of an inscrutable future |
| 45% | PTOLEMY | 7 | Greek, posited a geocentric theory of the universe |
| 45% | YLEM | 4 | Primordial matter of the universe, according to the Big Bang theory |
| 45% | PSALM | 5 | One begins "By the rivers of Babylon, there we sat down" |
| 45% | BIGBANG | 7 | A theory that explains the origin of the universe |
| 45% | ADM | 3 | Ackbar of the "Star Wars" universe, for one (abbr.) |
| 44% | ROCKETMAN | 9 | 2019 music biopic that tells the story of how 17-Across began collaborating with 27-Across |
| 44% | YOUNGSHELDON | 12 | "The Big Bang Theory" prequel about one of the scientists as a boy (2 wds.) |
| 44% | NEEDLE | 6 | Put thread through the eye of one to begin sewing |
| 44% | QUASAR | 6 | One of a number of astronomical bodies thought to be the most luminous objects in the universe |
| 43% | SONNET | 6 | One of Shakespeare's begins "My mistress' eyes are nothing like the sun" |
| 43% | LUCKYTOBECLIVE | 14 | How novelist Cussler felt when one of his books hit the bestseller list? |
| 43% | AWE | 3 | What one feels when staring at the vastness of the universe |
| 43% | VCR | 3 | ___ revolution, one of the defining landmarks of '80s TV that changed how everyone watched TV: Abbr. |
| 43% | EMAIL | 5 | An automated one might begin "I'm out of the office until ..." |