| 100% | ENRICO | 6 | Opera singer Caruso whose “Vesti la giubba” was the first record to sell a million copies |
| 37% | BEETLE | 6 | Volkswagen model which has the record of being the first car to sell 20 million units |
| 35% | ERNANI | 6 | Verdi work that was the first opera to be recorded in its entirety |
| 35% | BIGMAMATHORNTON | 15 | Singer who was the first to record “Hound Dog” |
| 35% | BSMITH | 6 | Transcultural icon whose home collection was the first by a Black woman to be sold at a major retailer |
| 34% | RENEE | 5 | Fleming who was the first opera singer to perform the national anthem at the Super Bowl (2014) |
| 33% | MOTOROLA | 8 | The first company to sell a cellphone, in 1973 |
| 32% | DANDRIDGE | 9 | Singer Dorothy who was the first African-American to get a Best Actress Oscar nomination |
| 32% | WIN | 3 | Be the first one to finish a race, say |
| 31% | FAITHHILL | 9 | "Speak to a Girl" singer whose first name is a positive virtue (belief): 2 wds. |
| 31% | PLATINUM | 8 | Designation for records that sell a million copies |
| 31% | JOEYFATONE | 10 | Former 'N Sync singer whose first name is also the term for a baby kangaroo: 2 wds. |
| 30% | MASSACHUSETTS | 13 | State whose General Court was the first to recognize Fourth of July as a state celebration |
| 30% | KURTISBLOW | 10 | Singer whose 1980 single "The Breaks" was the first gold record rap song |
| 30% | GLENNM | 6 | Musician with the first record formally certified as a million-seller |
| 30% | SALONGA | 7 | Lea who was the first Asian actress to win a Tony |
| 30% | SAMSMITH | 8 | "Stay With Me" singer who was a first-time Grammy nominee for Record of the Year (and won): 2 wds. |
| 30% | MELISSAFUMERO | 13 | "Brooklyn Nine-Nine" actress whose first big role was Adriana Cramer on the soap opera "One Life to Live" (2 wds.) |
| 30% | MAHALIA | 7 | Jackson who was the first gospel singer to perform at Carnegie Hall |
| 30% | DEMILOVATO | 10 | "Heart Attack" singer whose first TV series lead role was on the Disney Channel's "Sonny with a Chance": 2 wds. |
| 29% | TEBOW | 5 | Tim who was the first sophomore to win a Heisman |
| 29% | BESSEL | 6 | German astronomer who was the first to measure the distance to a star |
| 29% | SPOTIFY | 7 | Music streaming platform where Taylor Swift set a world record for being the first female artist to amass 100 million monthly listeners |
| 29% | POITIER | 7 | Sidney who was the first African-American to win a Best Actor Oscar |
| 29% | PALM | 4 | Co. that was the first to successfully market a PDA worldwide in 1997 |
| 29% | ETHEL | 5 | Waters who was the first Black American to host a national television show |
| 29% | BASIE | 5 | Jazz great who was the first African-American man to win a Grammy |
| 29% | POITIER | 7 | Sidney who was the first African American to win a Best Actor Oscar |
| 29% | LORRE | 5 | Peter who was the first actor to play a Bond villain |
| 29% | EVE | 3 | Her first recorded words were spoken to a snake |