| 100% | NRA | 3 | Org. targeted by a 2018 boycott |
| 48% | SSN | 3 | ID targeted by a phisher |
| 48% | LAT | 3 | Muscle targeted by a pullup |
| 47% | PORES | 5 | Openings targeted by a facial cleanser |
| 47% | PATSY | 5 | Sucker targeted by a con artist |
| 47% | QUAD | 4 | Thigh muscle targeted by a squat, slangily |
| 47% | PEC | 3 | Muscle targeted by a chest press, informally |
| 46% | OFEFFECT | 8 | Spot that is targeted by a spell: Area __ |
| 46% | CORE | 4 | Muscles targeted by a dead bug (Wait ... what?!) |
| 45% | NRA | 3 | Org. targeted by Moms Demand Action |
| 44% | GAMESTOP | 8 | Company whose stock was targeted by a 2021 short squeeze |
| 44% | NUCOOWERPLANTS | 14 | Energy producers targeted by a famous 1979 rock concert series |
| 43% | ACDC | 4 | Rock band commemorated by a 2018 series of Australian postage stamps |
| 42% | IRS | 3 | Org. addressed by a 64-Down |
| 41% | EPA | 3 | Org. established by a Nixon executive order |
| 41% | BPOE | 4 | Org. led by a Grand Exalted Ruler |
| 41% | GHOSTS | 6 | Kids See them in a 2018 side project by Ye |
| 41% | EPA | 3 | Org. headed by Scott Pruitt until July 2018 |
| 41% | NSA | 3 | Org. symbolized by an eagle holding a key |
| 40% | MLS | 3 | Org. with a team owned by 10-Down |
| 39% | DSA | 3 | Political org. symbolized by a rose |
| 38% | KONG | 4 | 2018 Broadway role ''played'' by more than a dozen people simultaneously |
| 37% | THEFBI | 6 | Law org. led by Christopher A. Wray since 2017 |
| 37% | NEA | 3 | Org. once chaired by Jane Alexander with a name hidden in Jane Alexander |
| 36% | MONEY | 5 | "Dirty ___," a 2018 Netflix docuseries by Alex Gibney covering corporate corruptions and interviews with key players |
| 35% | DAVID | 5 | ___ Hockney, queer artist behind the most expensive artwork by a living artist to be auctioned in 2018 |
| 35% | THELIBRARYBOOK | 14 | 2018 nonfiction work by Susan Orlean about a devastating fire in Los Angeles (3 wds.) |
| 35% | TRE | 3 | Cornerback Flowers selected by the Seahawks as a safety in the 2018 draft |
| 35% | NORAD | 5 | Org. always headed by a U.S. general or admiral |
| 35% | COULDVEBEEN | 11 | Was almost possible, or a 2018 R&B hit by H.E.R. featuring Bryson Tiller: 2 wds. |