| 100% | DANAYKROYD | 10 | Original "Saturday Night Live" cast member who appeared in "Point-Counterpoint" sketches with 17-Across (2 wds.) |
| 92% | JANECURTIN | 10 | Original "Saturday Night Live" cast member who appeared in "Point-Counterpoint" sketches with 39-Across (2 wds.) |
| 58% | GARRETTMORRIS | 13 | Original "Saturday Night Live" cast member who plays the cashier on 15-Across' show: 2 wds. |
| 56% | JOHNBELUSHI | 11 | Original "Saturday Night Live" cast member who played a samurai: 2 wds. |
| 56% | JANECURTIN | 10 | Original "Saturday Night Live" cast member who played Mrs. Loopner: 2 wds. |
| 56% | GILDARADNER | 11 | Original "Saturday Night Live" cast member who played Emily Litella: 2 wds. |
| 56% | DANAYKROYD | 10 | Original "Saturday Night Live" cast member who played the Coneheads dad: 2 wds. |
| 53% | ANDYSAMBERG | 11 | "Saturday Night Live" cast member who recently ended his seven-year run with the show: 2 wds. |
| 53% | KRISTENWIIG | 11 | "Saturday Night Live" cast member who recently ended her seven-year run with the show: 2 wds. |
| 52% | KATEMCKINNON | 12 | "Saturday Night Live" cast member who plays talent agent Debra Hammer in 41-Across (2 wds.) |
| 52% | CHRISROCK | 9 | "Saturday Night Live" cast member (1990-1993) who voiced the zebra Marty in the "Madagascar" movies: 2 wds. |
| 52% | KENANTHOMPSON | 13 | Comedian and "Saturday Night Live" cast member who voices Gus the beaver in 43-Across (2 wds.) |
| 49% | JASONSUDEIKIS | 13 | "Saturday Night Live" cast member who threatened to end his seven-year run with the show but is back for the 2012-2013 season: 2 wds. |
| 46% | EGO | 3 | Former Saturday Night Live cast member who announced her departure from the show in a September Instagram post |
| 46% | ANDYSAMBERG | 11 | Former "Saturday Night Live" cast member who plays 34-Across on 15-Across/41-Across (2 wds.) |
| 45% | BILLHADER | 9 | Former "Saturday Night Live" cast member who plays the title role on 4-Across (2 wds.) |
| 44% | KATEMCKINNON | 12 | "Saturday Night Live" cast member who voices Squeeks the Mouse on PBS Kids' "Nature Cat" (2 wds.) |
| 43% | TRACYMORGAN | 11 | Former "Saturday Night Live" cast member who hosted the 2019 ESPY Awards ceremony (2 wds.) |
| 42% | ANDYSAMBERG | 11 | Former "Saturday Night Live" cast member who plays Jake Peralta on "Brooklyn Nine-Nine" (2 wds.) |
| 42% | ADAMSANDLER | 11 | Comedian and former "Saturday Night Live" cast member: 2 wds. |
| 41% | KENANTHOMPSON | 13 | Actor who is the longest-running Saturday Night Live cast member, born after the premiere of SNL (42nd anniversary today): 2 wds. |
| 41% | PETEDAVIDSON | 12 | "Saturday Night Live" cast member who was a regular guest on MTV's "Nick Cannon Presents Wild 'N Out" (2 wds.) |
| 41% | FREDARMISEN | 11 | Former "Saturday Night Live" comedian who cocreated and frequently appears on 34-Across: 2 wds. |
| 40% | KATEMCKINNON | 12 | "Saturday Night Live" actress who co-stars with Mila Kunis in "The Spy Who Dumped Me" (2 wds.) |
| 40% | AMYPOEHLER | 10 | "Saturday Night Live" comedian who went on to star in 24-Across and 36-/42-Across: 2 wds. |
| 40% | BARACKOBAMA | 11 | President who comedically appeared in a 2007 episode of "Saturday Night Live": 2 wds. |
| 39% | COLINJOST | 9 | "Saturday Night Live" writer who married actress Scarlett Johansson in 2020: 2 wds. |
| 39% | NORMMACDONALD | 13 | "Saturday Night Live" comedian who voiced the dog Lucky in "Dr. Dolittle": 2 wds. |
| 39% | DAN | 3 | Original "Saturday Night Live" cast member Aykroyd |
| 39% | GILDA | 5 | Original "Saturday Night Live" cast member Radner |