| 100% | DIRAC | 5 | Paul, who in 1928 came up with the equation that predicted antimatter |
| 40% | EINSTEIN | 8 | He came up with the equation "E = mc²" |
| 39% | TODDRUNDGREN | 12 | Singer who came up with "Bang the Drum All Day" in his sleep: 2 wds. |
| 35% | DIRAC | 5 | Paul who shared the 1933 Nobel Prize in Physics with Schrödinger |
| 35% | MICHAELSTIPE | 12 | Singer who came up with "It's the End of the World as We Know It (And I Feel Fine)" in his sleep: 2 wds. |
| 35% | MASLOW | 6 | Psychologist Abraham who came up with his principle in 1966 that "if all you have is a hammer, everything looks like a nail" |
| 35% | GAL | 3 | "Keeping up with the Joneses" actress Gadot, who plays Wonder Woman in 31-Across |
| 34% | EINSTEIN | 8 | Physicist Albert who came up with the special theory of relativity |
| 33% | ERR | 3 | Come up with the wrong answer |
| 33% | PAULMCCARTNEY | 13 | Singer who came up with "Yesterday" in his sleep: 2 wds. |
| 33% | TSA | 3 | Org. with jurisdiction that's up in the air |
| 32% | DRE | 3 | Dr. who came up with "Nuthin' but a 'G' Thang" in 1992 |
| 32% | DRAWINGABLANK | 13 | Failing to come up with the answer |
| 31% | ADLIB | 5 | Come up with, on the spot: Hyph. |
| 30% | GUESSWORK | 9 | Coming up with a theory without the full facts |
| 30% | MARSFORINSTANCE | 15 | Come up in the world? |
| 30% | ARLEN | 5 | Harold, the composer who came up with "Ding-Dong! The Witch Is Dead" |
| 30% | MARYTRAVERS | 11 | Folk singer who, in a trio with Peter and Paul, sang the 1963 hit "Puff, the Magic Dragon": 2 wds. |
| 30% | BERRA | 5 | Yankee Yogi who's credited with saying "When you come to a fork in the road, take it" |
| 29% | HEISENBERG | 10 | Quantum mechanics pioneer Werner, who came up with his uncertainty principle in 1927 |
| 29% | CHARLOTTESWEB | 13 | Children's classic with the line "It is not often that someone comes along who is a true friend and a good writer" |
| 29% | CONTENTS | 8 | Page that lists what's coming up in the book |
| 29% | ETC | 3 | Car that succeeded the Cadillac Biarritz in 1992 and came with Zebrano-trimmed full-floor console with shifter (abbr.) |
| 29% | XAXIS | 5 | It lines up with the line y = 0, in math |
| 29% | DANAE | 5 | Princess who became pregnant with Perseus after Zeus came to her in the form of a shower of gold |
| 29% | GLOVES | 6 | I'm the second skin that protects chemist's hands and I always come in pairs. Who am I? |
| 29% | DANO | 4 | Paul who plays the Riddler in "The Batman" |
| 29% | KRIS | 4 | Jenner who is the matriarch in "Keeping Up with the Kardashians" |
| 29% | SOLE | 4 | Shoe part that comes in contact with the ground |
| 28% | RUDD | 4 | Paul who played the title role in “Our Idiot Brother” |